Structurally, phosphatidylserine is an amino acid that consists of glycerophosphate
skeleton conjugated with two fatty acids and L-serine via a phosphodiester linkage.
Among these materials, the use of potassium oxalates, (5) sodium fluoride, (6) strontium salt, (2) amorphous calcium phosphate containing casein phosphopeptide; (7) calcium glycerophosphate
, (8) and calcium carbonates (mainly as abrasive agents) (9) have gain significant interest as an occlusion materials.
In contrast, isobutyl xanthine and beta glycerophosphate
in the presence of BMP-2 have been found to promote adipogenic and osteogenic differentiation, respectively.
Rahimi et al., "Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate
dehydrogenase," Nature, vol.
They combine adhesive and composite technology because it contains glycerophosphate
dimethacrylate (GPDM) monomer adhesive and acidic phosphate group as found also in other adhesive system.
showed that acute and chronic metformin actions reduce endogenous glucose production by raising the cytosolic redox state and decreasing the mitochondrial redox state through noncompetitive inhibition of mitochondrial glycerophosphate
In addition to NDH, metformin was shown to inhibit other enzymes of the mitochondrial oxidative phosphorylation apparatus, including mitochondrial glycerophosphate
dehydrogenase (mGPDH) and ATP synthase [7, 10, 23].
The alkaline phosphatase (ALP) substrate p-nitrophenol phosphate (p-NPP), 8-hydroxyquinoline, o-cresolphthalein, 2-amino-2-methylpropan-1-ol (AMP), dexamethasone, glycerophosphate
, and ascorbic acid (AA) were also obtained from Sigma.
Participation of one isozyme of cytosolic glycerophosphate
dehydrogenase in adipose conversion of 3T3 cell.
Summary of NaOH/EDTA extractable P forms (in mg/kg) as determined by [31.sup.P] NMR spectroscopy and quantified using spectral deconvolution Ortho-P, Orthophosphate; Lipid, [alpha]-glycerophosphate and [beta]- glycerophosphate
; RNA-sum of up to four individual resonances in the chemical shift range 3.93-4.47 ppm; scyllo-[IP.sub.6], scyllo- Inositol hexakisphosphate; Pyro-P, pyrophosphate.
In recent years, further probable mechanisms involved in cAMP, the phosphorylation of Acc1 and Acc2, mitochondrial glycerophosphate
dehydrogenase, and the activated duodenal AMPK were found to affect metformin's effect in different ways [3-6].