glycocalyx


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glycocalyx

[′glī·kō′kā‚liks]
(cell and molecular biology)
The outer component of a cell surface, outside the plasmalemma; usually contains strongly acidic sugars, hence it carries a negative electric charge.
References in periodicals archive ?
Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx. J Am Soc Nephrol.
Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer.
Analysis of 242-282 nm range wavelength spectrograms for low and medium molecular weight substances in plasma and red blood cells glycocalyx indicates significant difference between experimental and control groups.
electrically charged glycocalyx, the presence of one or more tight
Liu, "Dexamethasone suppressed LPS-induced matrix metalloproteinase and its effect on endothelial glycocalyx shedding," Mediators of Inflammation, vol.
Neumann, "Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx," Glia, vol.
These processes affect cell-surface adhesion molecules and disrupt the glycocalyx layer.
N-glycan patterns of the plasma membrane glycoproteins contribute a large amount to the glycosylation of the glycocalyx. Like a tag, the total N-glycan pattern on the cell surface produces specific markers for the types of embryonic differentiation and aging stages and physiological and pathological state of the cells.
(112) Biofilms are formed when microorganisms adhere to surfaces, typically through the secretion of a polysaccharide substance referred to as the glycocalyx. (113) The movement of water over the surface can cause parts of the biofilm to dislodge and resuspend in the water.
However, it can be detrimental and life-threatening when administered in high volumes, and we have to stress the importance that distribution within the body of critically ill patients is unpredictable due to glycocalyx injury and disturbances of lymphatic flow, fluids are leaving vascular bed and escape to the interstitium (23).
But owing to the less number of researches being carried out in this domain, the exact function of these halo sugars (glycocalyx) was unknown.