QUA1 Regulates Chloroplast-Associated Calcium Signaling During Salt and Drought Stress in Arabidopsis.
Purification and characterization of a cyclodextrin glycosyltransferase
from Paenibacillus sp.
X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase
elucidate catalysis in the [alpha]-amylase family.
[ClickPress, Thu Sep 20 2018] Glycomics/Glycobiology Market by Product (Enzymes (Glycosyltransferase
, Glycosidase), Instruments (HPLS, Mass Spectrometry, MALDITOF), Kits & Reagents (Glycoproteins)), Application (Diagnostic, Drug Discovery, Oncology), End User - Global Forecast to 2021 The global glycomics market is poised to reach USD 1,211.4 Million by 2021 from USD 649.5 Million in 2016, at a CAGR of 13.3%.
ABO, Le, and secretor genes control the enzyme glycosyltransferase
attach sugar molecules to disaccharide precursors and build oligosaccharide structures on the cell surface of red blood cells and vascular endothelium as well as in the exocrine secretion system, including the respiratory tract.
This mechanism is corroborated by the observation that individuals with non-O blood group have circulating levels of both VWF and FVIII that are approximately 25% higher than those in O blood group subjects ; the presence of ABH antigenic structures on circulating VWF modulates their activity through specific glycosyltransferase
Burchell et al., "Nomenclature update for the mammalian UDP glycosyltransferase
(UGT) gene superfamily," Pharmacogenetics and Genomics, vol.
LpxB is the glycosyltransferase
that forms the base glucosamine disaccharide of lipid A, catalyzing the formation of the glycosidic bond between the anomeric carbon of the UDP-DAG glucosamine and the 6-hydroxyl of lipid X to form lipid A disaccharide .
The enzymes responsible for these alterations are regulated by oncogenic growth factor signaling and represent novel therapeutic targets for cancer diagnostic and therapeutic strategies, such as the development of glycosyltransferase
inhibitors, glycomimetics, and glycan/glycopeptide-based vaccines .
"Common variation in the ABO glycosyltransferase
is associated with susceptibility to severe Plasmodium falciparum malaria." Human molecular genetics 17.4 (2008): 567-576. (http://hmg.oxfordjournals.org/content/17/4/567.full.pdf+html) Common variation in the ABO glycosyltransferase
is associated with susceptibility to severe Plasmodium falciparum malaria
overexpression is a tumor hallmark and can be used as a tumor marker .