glyoxalase
Also found in: Medical.
glyoxalase
[glī′äk·sə‚lās] (biochemistry)
An enzyme present in various body tissues which catalyzes the conversion of methylglyoxal into lactic acid.
Also found in: Medical.
References in periodicals archive
?
Newer experiences demonstrate that higher levels of MGO, the MGO derived AGEs (MGO-AGE) and hydroimidazolone-1 (MGO-H1), along with dysfunctioning framework of glyoxalase are connected to a few age-related medical issues including certain cardiovascular problems, diabetes, disorders of central nervous system and cancer.
Exogenous pro line and glycine betaine mediated upregulation of antioxidant defense and glyoxalase systems provides better protection against salt-induced oxidative stress in two rice (Oryza sativa L.) varieties.
Exogenous proline and glycine betaine mediated upregulation of antioxidant defense and glyoxalase systems provides better protection against salt-induced oxidative stress in two rice (Oryza sativa L.) varieties.
Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I.
In addition, Ni can activate an isoform of glyoxalase I that catalyze an important step in the degradation of methylglyoxal (MG), a compound naturally produced by cellular metabolism that may be lethal to cell functions.
Exogenous nitric oxide alleviates high temperature induced oxidative stress in wheat ( Triticum aestivum L.) seedlings by modulating the antioxidant defense and glyoxalase system.
(31) demonstrated that oleanolic acid (0.1 and 0.2%) and ursolic acid (0.1 and 0.2%) markedly suppressed renal aldose reductase activity and enhanced glyoxalase I activity, which contributed to decrease renal advanced glycation end products formation and improvedd renal functions.
Enzyme D-isomer specific 2-hydro xyacid dehydrogenase, whose expression levels was altered only in the Bolivia strain (Table 3, spot 3), was one of the proteins identified in the present work This enzyme is responsible to catalyze the NAD-dependent oxidation of R-lactate to pyruvate and is part of the detoxification pathway of methylglyoxal (dependent of glyoxalase I, glyoxalase II and low molecular mass thiols) in trypanosomatids, and data from Trypanosoma conorhini and Crithidia fasciculata showed activation in the presence of cysteine.
Creighton, "Inhibition by active site directed covalent modification of human glyoxalase I," Bioorganic & Medicinal Chemistry, vol.
gloA encodes glyoxalase I, an (R)-S-lactoylglutathione methylglyoxal lyase (isomerizing) activated by Zn(II) or Ni(II) ions, and is 411 bp (136 amino acids) in length.
Zhou, "Methylglyoxal as a novel signal molecule induces the salt tolerance of wheat by regulating the glyoxalase system, the antioxidant system, and osmolytes," Protoplasma, vol.
reduced activity of the enzyme glyoxalase (which is deficient in
Encyclopedia browser
?
- ▲
- glycosidase
- glycoside
- Glycosides
- glycosphingolipid
- glycosuria
- glycosyl
- glycosyl glyceride
- glycosyl phosphatidylinositol
- glycosylation
- glycosyltransferase
- glycotropic
- glycuresis
- glycuronic acid
- glycuronidase
- glycuronide
- glycyl
- glycyl alcohol
- Glycyrrhiza
- glycyrrhiza glabra
- Glyndebourne
- Glyndebourne Festival
- Glyndebourne Festival Opera
- Glyndebourne Festivals
- Glynn County
- Glyoxal
- glyoxalase
- glyoxalic acid
- glyoxylate cycle
- glyoxylic acid
- glyoxysome
- glyph
- Glyphocyphidae
- glyphosate
- glyphosine
- Glyphs
- Glypnir
- glyptal resin
- Glyptic
- Glyptocrinina
- Glyptodonts
- Glyptogenesis
- glyptolith
- glyptopleura marginata
- glyptotheca
- Glyptothek
- gm
- GM counter
- Gmail
- Gmail labels
- Gmail tabs
- Gmail Tap
- ▼
Full browser
?
- ▲
- Glyndebourne Festival Opera
- Glyndebourne festivals
- Glyndebourne festivals
- Glyndebourne House
- Glyndebourne House
- Glyndebourne Opera
- Glyndebourne Opera Festival
- Glyndebourne Opera House
- Glyndebourne Opera House
- Glyndwr
- Glyndwr
- Glyndwr
- Glynebourne
- Glynebourne
- Glynebwy
- Glynebwy
- GLYNI
- Glynis Barrie
- Glynis Barrie
- Glynn Academy
- Glynn County
- Glynn County Association of Educators
- Glynn County Fire Department
- Glynn County, GA
- Glynn County, Georgia
- Glynn Teachers Federal Credit Union
- Glyoxal
- Glyoxal
- Glyoxal
- Glyoxal-Bis-Hydroxyanil
- glyoxalase
- Glyoxalic
- glyoxalic acid
- glyoxaline
- glyoxaline
- glyoxaline
- Glyoxime
- Glyoxisome
- Glyoxisome
- Glyoxylate
- Glyoxylate
- Glyoxylate cycle
- Glyoxylate cycle
- Glyoxylate cycle
- glyoxylate transacetylase
- Glyoxylates
- Glyoxylates
- glyoxyldiureide
- glyoxyldiureide
- glyoxyldiureide
- Glyoxylic acid
- Glyoxylic acid
- Glyoxylic acid
- Glyoxylic acid cycle
- Glyoxylic acid cycle
- Glyoxylide
- Glyoxysome
- Glyoxysome
- Glyoxysomes
- Glyoxysomes
- GLYP
- ▼