Guidry, "A method for counterstaining tissues in conjunction with the
glyoxylic acid condensation reaction for detection of biogenic amines," Journal of Histochemistry & Cytochemistry, vol.
Tolbert, "Oxidation of
glyoxylic acid to oxalic acid by glycolic acid oxidase," The Journal of Biological Chemistry, vol.
The catecholamines have been demonstrated in olfactory neuroblastoma by fluorescent techniques after formaldehyde vapour or
glyoxylic acid treatment.
Nine a-keto acids:
glyoxylic acid (GA), pyruvic acid (PYR), 2- oxobutyric acid (KB), 3-methyl-2-oxobutyric acid (MKBA), 3-methyl-2-oxovaleric acid (K3MVA), 2-oxoglutaric acid (KG), 4-methyl-2-oxovaleric acid (K4MVA), 2-oxohexanoic acid (KHA) and phenylpyruvic acid (PPY) were derivatized with (NPD) at pH 3 and separated on a Zorbax 300 SB-C18 HPLC column (4.6x150mm id) and photodiode array detection at 255 nm.
The HAAs dichloroacetic acid, bromochloroacetic acid, and dibromoacetic acid are transformed to
glyoxylic acid, and 2,2-dichloropropanoic acid is metabolized to pyruvic acid (Board and Anders 2005).
Accumulation of glycolic Acid and
glyoxylic acid in serum in cases of transient hyperglycinemia after transurethral surgery.