56) Chickens fed a probiotic with multiple bacterial species showed a significant increase in goblet cells
In the present study, we show that gestational but not early postnatal exposure of mice to secondhand cigarette smoke (SS) suppresses alveolarization, angiogenesis, and development of Clara and goblet cells
without significant lung inflammation and that the SS-induced effects on alveolar architecture are irreversible.
The goblet cell
counts for the mid intestine were discounted as a result of the lack of goblet cells
present in this section of tissue.
The surface layer is composed of ciliated epithelial cells and mucus-secreting goblet cells
were slightly reduced in number but still deeply stained with PAS.
This gene has been detected in goblet cells
within the tracheal and bronchial epithelium of mice when metaplasia of mucous cells is present (Leverkoehne and Gruber 2002) and is thought to play a role in the mucus hyper-secretion seen in chronic obstructive pulmonary disease (COPD) and CF in humans (Rogers 2003; Shale and Ionescu 2004).
Mucin2 (MUC2) is the major mucin, produced and secreted by the goblet cells
in the intestinal epithelial tissue.
The dryness results in part from a loss of goblet cells
, which reappear after vitamin A deficiency is corrected.
The significant goblet cell
hyperplasia found in exposed subjects of our study, together with a clear increase of leukocytes (Figures 2 and 3), can be taken as an indication of a chronic state of irritation of the nasal mucosa with an inflammatory response (chemical-induced rhinitis) (30).
Treatment with Kp and QE reduces airway inflammation and goblet cell
9-12) Nongoblet columnar epithelium in the distal esophagus also shows DNA content abnormalities at rates comparable to those of esophageal goblet cells
, indicating that esophageal cardiac-type epithelium from patients with Barrett esophagus may already be "intestinalized," despite the absence of morphologic goblet cell
Glucocorticoids inhibit many of the cells involved in airway inflammation, including macrophages, T lymphocytes, eosinophils, and mast cells in the bronchial airway epithelium and submucosa, and reverse the shedding of epithelial cells and goblet cell
hyperplasia seen in asthma.