Further studies are needed to determine the susceptibility of gonococci
to gentamicin in different parts of the world and to establish the minimum dosage that will maintain sustainable cure rates.
By 1944, however, many gonococci
had become resistant to sulphanilamide and treatment failure was observed in over 30% of patients.
Moreover, our method could be a valuable molecular tool in an effective antimicrobial strategy to control gonococci
In addition to its lubricating properties, Amphora has been shown, in early clinical and pre-clinical tests, to immobilize sperm for up to eight hours when applied vaginally by women, and, in laboratory testing, to inactivate certain sexually transmitted infection-causing organisms including gonococci
(gonorrhea), herpes, chlamydia, and HIV.
There is only a report of naturally occurring gonococci
expressing a hybrid porB1a/porB1b (7) (PorBla and PorBlb gonococcus porins, as in meningococci, are encoded by 2 families of diverged alleles of the porB gene ).
Studies also confirmed the safety of Amphora in women when used consecutively for six days; and in animals for the prevention of the transmission of Gonococci
, Herpes and Chlamydia.
The problem of drug-resistant gonococci
has been growing in the U.
In meningococci as well as in gonococci
, the mutation at position 91 causes fluoroquinolone resistance.
For instance, in 1952, a famous French microbiologist anticipated pneumococci, gonococci
, and meningococci would not change their antimicrobial susceptibility profile in the future ("Pour une espece qui au depart etait entierement sensible .
are also increasing in Japan, as in south Asian countries (26).
These studies have also indicated that CEM-101 is active against atypical bacteria, such as Legionella, Mycoplasma and Ureaplasma and against gonococci
and other organisms that cause genitourinary tract infections.