primordial germ cell

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primordial germ cell

[prī¦mȯrd·ē·əl ′jərm ‚sel]
(embryology)
Embryonic cell giving rise to a germ cell from which a gamete (egg or sperm) develops.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The researchers therefore wanted to test which other molecular pathways might be responsible for the reduction in gonocyte number that they observed.
Primary germ cells (gonocytes) were located in the center of the cords.
In the human fetal testis, in culture (first trimester) the effect on GC number resulted from a reduction in the [TFAP2C.sup.+] gonocyte population, whereas in xenografts (second trimester) the reduction in germ cell number appeared to involve [TFAP2C.sup.+] and more differentiated prespermatogonia ([MAGEA4.sup.+]).
Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma.
DEHP/DBP exposure also induces germ cell effects in the fetal rat testis, namely, induction of multinucleated gonocytes (MNGs) (Ferrara et al.
CIS have both stemand germ-cell properties and originate from undifferentiated gonocytes because of poor function of Sertoli and/or Leydig cells during testis development.
The cells within region of GE were not properly differentiated and were distributed virgoursly in both groups comprising of both Sertoli cells and Gonocytes. The sertoli cells were somewhat polygonal in shape and their cytoplasm was homogenous.
Additionally, immature germ cells show morphologic features of primordial germ cells or gonocytes and, as such, have large nuclei, prominent nucleoli, and pale to lightly eosinophilic cytoplasm (Figure 1, B).
The primitive SG-A cells contain both SSCs and gonocytes, while SG-A cells are mostly differentiating SG with a small proportion of stem cells.
During male embryogenesis, primordial germ cells (PGCs) derived from the epiblast relocate in the genital ridges and experience differentiation into gonocytes (McLaren, 2003).