Many of these
Gram-negative pathogens are particularly worrisome because they are becoming resistant to nearly all drugs, including the carbapenems, often considered the last line of defense in these challenging infections.
Gram-negative bacterial toe web infection: a survey of 123 cases from the district of Cagliari, Italy.
Specifically disrupts lipids found in
Gram-negative bacteria membranes while not affecting membranes in eukaryotic cells--cells with the nucleus and other structures enclosed in separate membranes found in mammals and other nonmicrobial life.
In particular, Xellia is the world leading supplier of Vancomycin and CMS which together combat life-threatening, antibiotic-resistant bacterial infections across Gram-positive and
Gram-negative species.
In its most recent studies, which also appear this week in PNAS, the MD Anderson team found that D-KLAKLAK-2 is an effective killer of
Gram-negative bacterial pathogens, including several types that have grown resistant to traditional antibiotics.
Clinical Cure by Organism Ceftaroline Vanco/Az Gram-positive Staphylococcus aureus 93% 95% MRSA 95% 95% MSSA 91% 95% Streptococcus pyogenes 100% 100% Streptococcus agalactiae 93% 100% Enterococcus faecalis 93% 92%
Gram-negative Escherichia coli 90% 87% Klebsiella pneumoniae 91% 100% Proteus mirabilis 70% 90% Pseudomonas aeruginosa 100% 90% Note: Based on a study of 244 patients who received ceftaroline and 227 who received vancomycin/aztreonam (vanco/az).
is engaged in the discovery and development of novel antibiotics against multidrug-resistant
Gram-negative bacteria.
In three separate surveillance studies (E-0112, E-0115, E-0117) ceftobiprole was amongst the most potent cephalosporins against Enterobacteriaceae and Pseudomonas -- the most common
Gram-negative bacterial pathogens associated with hospital-acquired infections -- explained in part by its enhanced affinity for the penicillin-binding protein 2 (PBP2) in pseudomonads (C1-0933).
More likely, the patient acquired her almost completely resistant
gram-negative organism in the rural hospital or her local nursing home.
Blumberg is an epidemiologist, have been unable to eradicate some forms of persistent multidrug-resistant (MDR)
gram-negative bacteria, but they have developed strategies to reduce the risk of infections.
Histologically, lymph node aspirates are characterized by the presence of small, pleomorphic,
gram-negative, argyrophilic bacilli on Warthin-Starry staining.
Acticoat[R], from Smith & Nephew, is a silver-coated antimicrobial dressing that offers broad protection from more than 150 types of wound pathogens, including
gram-negative and gram-positive bacteria, fungal organisms, and antibiotic-resistant bacteria such as MRSA and VRE.
