3 July 2013 - US molecular diagnostics system developer Nanosphere Inc (NASDAQ:NSPH) reported Tuesday encouraging results for the diagnostic accuracy and potential clinical impact of its FDA-approved Verigene Gram-Positive
Blood Culture (BC-GP) Test.
The findings suggest that further studies are warranted to determine the agent's role in treating gram-positive
bone and joint infections, and to determine optimal dosing.
Although much attention has been focused on the progression of antimicrobial drug resistance in gram-positive
organisms, the development of alternative antimicrobial agents such as linezolid and daptomycin may mitigate the disastrous scenario of complete resistance to all commercially available antimicrobial agents.
Initial linezolid use also was a significant predictor of survival (odds ratio 1.6 overall; 2.6 among gram-positive
VAP patients; 4.6 among MRSA-VP patients), the investigators found (Intensive Care Med.
bacteria don't bind to the receptor, so the color doesn't change."
They found an improved preservative effect by nisin on Gram-positive
bacteria when the product was treated with nisin and essential oils--carvacrol, thymol and carvone from oregano; thyme; and caraway seeds.
* A snapshot of the global therapeutic scenario for Gram-Positive
The study included 1,267 patients who had complicated skin and skin structure infections that involved gram-positive
A report of "many Gram-negative rods" or "moderate Gram-positive
cocci suggestive of staphylococci" helps determine whether empiric antibiotics will be effective.
bacterial sepsis segment is likely to account for the maximum share in terms of revenue in the global market for sepsis diagnostics.
[USA], June 24 (ANI): Cannabidiol, the main non-psychoactive chemical compound extracted from cannabis and hemp plant, is found to be active against Gram-positive
bacteria including those cause serious infections, with a potency similar to established antibiotics, finds a recent study.
In a large, ongoing surveillance study of Xerava, researchers evaluated the in vitro activity of the drug against Gram-negative and Gram-positive
global isolates collected in 2017, including MDR pathogens.