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A discrete nodular lesion of inflammatory tissue in which granulation is significant.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Diagnosed as an isolated solitary orbital eosinophilic granuloma, our patient received 12 cycles of vinblastine chemotherapy without evidence of any complications and without evidence of any recurrence over the 2 years of follow-up.
The most common type of granuloma was tuberculous granulomas 63 (73.28%) followed by granuloma of cutaneous leishmaniasis 08 (9.30%), fungal granulomas 05 (5.81%), foreign body granulomas 04 (4.65%), leprosy 03 (3.84%) and one each (1.16%) of necrobiotic granuloma, sarcoid granuloma and malakoplakia.
The most common pathology among them is the peri-apical granuloma, comprised by a mass of chronic inflammatory tissue, in which isolated nests of epithelium can be found.
Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp.
A granuloma is an organised structure consisting of highly differentiated cells such as multi-nucleated giant cells, epithelioid cells and foamy cells surrounded by lymphocytes.
The two specimens (before and after FDT), were compared with respect to the basement membrane pigmentation, percentage of dermis occupied by granuloma or inflammatory infiltrate per average low power field, presence of protective cells such as lymphocytes and epithelioid cells, the presence of acid fast bacilli and evidence of dermal fibrosis.
Lobular capillary hemangioma (pyogenic granuloma) occurs in all age groups, children to older adult, but are more frequently encountered in females in their second decade due to hormonal changes.
A study revealed that granuloma annulare might be caused by a delayed-type hypersensitivity reaction.
El diagnostico clinico de periodontitis apical expresado en su forma de quiste radicular o granuloma periapical corresponde en ambos casos a dos etapas distintas del mismo proceso inflamatorio en la patogenesis de la lesion periradicular (Liapatas et al., 2003; Chi & Neville), por lo que resulta confuso de senalar en ocasiones, que ciertas celulas puedan estar asociadas exclusivamente o tener mayor predominio con uno u otro tipo de lesion.
The patient subsequently underwent microdirect laryngoscopy, excision of a left true vocal fold granuloma, angiolytic KTP laser treatment of the attachment site, and dexamethasone injection.