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A discrete nodular lesion of inflammatory tissue in which granulation is significant.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Market Research Future (MRFR) in its latest report, discusses the growth opportunities of the global chronic granulomatous disease market.
Chronic granulomatous disease is an X-linked or auto somal recessive condition that affects approximately 1 in 200,000-250,000 live births.
By the isolation of this bacteria, some authors preferred to use "Cystic Neutrophilic Granulomatous Mastitis" term for the IGM cases associated with gram-positive bacilli (10, 11).
Of note, this stain was only done if the pathologist found features of granulomatous inflammation or, in some cases, pleuritis.
[9] Granulomatous lymphadenitis was the commonest diagnosis in studies of Pandav et al [11] and Hafez et al.
Chronic granulomatous disease (CGD) is a rare genetic condition where nicotinamide adenine dineucleotide phosphate (NADPH) oxidase complex fails to generate reactive oxygen species (ROS) in the activated neutrophils, monocytes and macrophages.1 CGD is a single gene defect; either X-linked recessive (XR - CGD) in 60% of the cases or autosomal recessive (AR - CGD) in 40% of the cases.
The disease can occur as Miescher's isolated granulomatous cheilitis or with other granulomatous diseases (Crohn's disease, sarcoidosis and Melkersson-Rosenthal syndrome) (5,7).
Chronic granulomatous disease (CGD) is an immune deficiency condition that may present with variable systemic signs and symptoms, characterized by recurrent infections.
Aberrant calcium metabolism is related to sarcoidosis and other granulomatous disorders as a result of increased levels of active 1,25-dihydroxy vitamin D (OHD).
Granulomatous inflammation was reported in the lymph node after performing a Tru-cut biopsy on the pathologic formed lymph node in the right supraclavicular region.
Granulomatous mastitis has several treatment options, and although most cases respond to monotherapy, some patients require a combination of options (5).

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