griseofulvin


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griseofulvin

[‚griz·ē·ō′fu̇l·vən]
(microbiology)
C17H17O6Cl A colorless, crystalline antifungal antibiotic produced by several species of Penicillium. Also known as curling factor.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Friedlander highlights four potential systemic agents: griseofulvin, terbinafine, itraconazole, and fluconazole.
Griseofulvin acid 2 was synthesized as reported [20] through hydrolysis of griseofulvin 1.
Terbinafine (Lamisil[R]; batch number U0638; marketed by Novartis Pharma Ltd., United Kingdom), itraconazole (Canditral[R]; batch number 01141282; marketed by Glenmark Pharmaceuticals Ltd., India), griseofulvin (Griseon[R]; batch number 178046; marketed by Plus Five Pharmaceuticals Ltd., Zimbabwe), fluconazole (Flumyc200[R]; batch number AHP054014; marketed by Ipca Laboratories Ltd., India), and ketoconazole (Nizol[R]; batch number 13312; marketed by Intas Pharmaceuticals Ltd., India) were all sourced from a local pharmaceutical wholesaler.
The complexes 3'b, 3'c and 3'd have 250 [micro]g[mL.sup.-1] MIC value and 13 [+ or -] 3 mm ZOI, two times greater than the used reference drug griseofulvin, out of them, complexes 3'b and 3'c are more active than those of free ligands, whereas, 3'd complex have less activity than that of free ligand.
Nonaka, "Experimental murine protoporphyria induced by griseofulvin (GF): the relationship between hepatic porphyrin levels and liver function test values in mice treated with GF" Journal of Dermatology, vol.
With regard to treatment, we found that itraconazole and terbinafine were more effective than griseofulvin in the management of adult TC.
For the 12 months ended 30 June 2012, the US market sales for Griseofulvin tablets, an antifungal antibiotic that fights infections caused by fungus, were about USD13m, according to IMS Health data.
Extract Code Metabolites Corynesporacasiicola KK9L2-A Dechlorogriseofulvin KK9L2-B Griseofulvin Phomopsissp.
Currently, griseofulvin (Grifulvin[R]) and terbinafine (Lamasil Granules[R]) are the only two medications approved by the United States Food and Drug Administration (FDA) for the treatment of tinea capitis (FDA, 2007; Roberts & Friedlander, 2005).
Treatment options are relatively narrow using conventional drugs now that the in-feed medication, griseofulvin, has been removed from use in food producing animals.