growth cone


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growth cone

[′grōth ‚kōn]
(neuroscience)
A specialized structure at the end of a growing nerve fiber that guides the fiber to its destination during the development of the nervous system by means of interaction with signaling molecules in its surroundings and its own motile mechanism.
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44) Conversely, overexpression of MLK-1 improves the frequency and timing of growth cone formation, as well as the rate of successful migration of growth cones to their target sites.
As a circuit is being built, RNAs in the neuron's growth cones are mostly silent.
The role of cytoskeleton in organizing growth cones: a microfilament-associated growth cone component depends upon microtubules for its localization.
Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides.
The protein, actin, found in the growth cone membrane and within the cytoplasm, together with tubulin, the structural component of microtubules, provides the means to change the shape of the growth cone structure to move towards, or away from, the environmental cues.
Injecting a tracer into the cell body of the neuron means that over several days the tracer is transported along the axon and into the growth cone.
This appraisal details Bryan's introduction of short-term, aggregate growth cones for setting monetary policy as a means of achieving his longer-term targets and the opposition he faced within the FOMC.
Between the fourth quarter of last year and June, M2 expanded at an annual rate of almost 5 percent; as the Committee had anticipated, the aggregate was running close to the upper bound of its growth cone, which had been chosen to be consistent with price stability.
The presence of two unique membrane-associated phosphoproteins in growth cones is interesting in light of studies linking intracellular calcium ion and other second messengers to growth cone behaviour involved in synaptic remodelling in adult neurons.
The BioScope II mounts directly on an inverted optical microscope, so we were able to get high-resolution images of a neuron's growth cone using AFM that complement and extend the information from fluorescence microscopy," commented Dr.
Several research topics have emerged: (1) Recurrent mutations were detected in neuronal growth cone genes.