New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma
pentaphyllum was recently approved by the Therapeutics Goods Administration for use in listed medicines.
The list of supplements and foods that activate AMPK is extensive and includes persimmon, genistein, pomegranate vinegar, vinegar, blueberries, extra-virgin olive oil, cinnamon, fish oil, folic acid, Hugan Qingzhi, quercetin, grapeseed extract, astragalus, bitter melon, apiginin, resveratrol, curcumin, transtiliroside, rosehips, EGCG from green tea gallic acid, aspirin, hydrogen sulfide, chitosan, baicalin, gynostemma
pentaphyllum, and cocoa.
Genetic differentiation in endangered Gynostemma
Draco supplies a 20% berberine extract from the TCM herb Coptis chinensis and a Gynostemma
extract (30% saponins).
The active ingredient is based on two powerful plants: Gynostemma
pentaphyllum from the Far East activates LXR, a skin receptor involved in the synthesis of epidermal lipids.
The same effect was observed in hypercholesterolemic rats treated with aqueous extract of Gynostemma
pentaphyllum (Megalli et al.
pentaphyllum Makino, a perennial creeping herb grown prevalently throughout China, India, Japan and Korea (Blumer and Liu, 1999), is a traditional medicine widely used in the treatment of respiratory inflammation such as cough and chronic bronchitis (Tanner et al.
The treatment combines GABA, a muscle-relaxant, with extracts of the Chinese 'miracle herb' gynostemma
pentaphyllum, which is dubbed 'magic grass' because of its anti-ageing qualities.
John's wort) herb, Coptis chinensis (gold thread, huang han) root, Artemisia hudoviciana (western mugwort) leaf, Glycyrrhiza glabra (licorice) root, glycyrrhizin, Schisandra chinensis (wu wei zi) fruit, Astragalus membranaceus (huang qi) root, Taraxacum officinale (dandelion) root, Arctium lappa (burdock) root, shosaiko-to, Xiao Chai Hu Tang, Salvia miltiorrhiza (Chinese sage, dan shen) root, salvianolic acid B, Fuzheng Huayu formula, Gynostemma
pentaphyllum (jiao gu lan) root, and Ginkgo biloba seed.
A concentracao de Zn em diferentes plantas (Hibiscus sabdariffa (roselle), Ilex paraguariensis, Gynostemma
pentaphyllum e Morus alba) variou de 10 a 62 [micron]g.
Dr Philip Franks of Food Science Australia, and his colleagues in the CRC for Bioproducts, are investigating the use of hairy roots to mass-produce the active ingredients found in herbal medicines such as echinacea, ginseng and gynostemma