In the present study, ReHo analysis of the normal elderlies and aMCI patients revealed that in the resting state, ReHo values were significantly higher in the posterior cingulate gyrus
, the inner side of the frontal lobe, the inner side cortex of the prefrontal lobe, and part of the parietal lobe.
Then, the tissue slides were studied under an optic microscope for proliferated neurons counting in dentate gyrus
[Figures 2 and 3].
When they artificially increased RbAp48 in the dentate gyrus
of aging mice, the animals' memories improved, according to Kandel.
Before the intervention found that areas related to anomia were the superior frontal gyrus
, the angular gyrus
and the superior temporal gyrus
and a half I left mainly hemisphere.
It was found that the number of correct responses of Card C in the Stroop Color-Word Test was negatively correlated with the grey matter volumes of the upper lateral frontal gyrus
(r=-0.38), the right dorsolateral upper frontal gyrus
(r=-0.45), the upper left medial frontal gyrus
(r=-0.50), the right medial frontal gyrus
For the Inflation event, between-group comparisons revealed that SCZ + S patients had increased activations in the right cerebellar declive and lingual gyrus
in comparison to SCZ - S patients, as well as increased activations in the left superior temporal gyrus
in comparison to healthy participants.
As shown in Figure 1 and Table 2, the ReHo values were higher in depressed patients in the right superior temporal gyrus
, right middle temporal gyrus
, left inferior temporal gyrus
, left middle temporal gyrus
, right middle frontal gyrus
, triangular part of the right inferior frontal gyrus
, orbital part of the right inferior frontal gyrus
, right superior occipital gyrus
, right middle occipital gyrus
, bilateral anterior cingulate, and paracingulate gyri, and values were reduced in the right fusiform gyrus
, left middle occipital gyrus
, left lingual gyrus
, and left inferior parietal except for the supramarginal and angular gyri.
Perforant-path stimulation is a classical in vivo model to study synaptic transmission, long-term synaptic plasticity, and network excitability in the dentate gyrus
The DMN connectivity map for the ROI-to-ROI analysis showed lower connectivity in the patient group between PCC (seed region) and the frontal pole, paracingulate gyrus
, superior frontal gyrus
, and cingulum.
According to fMRI analysis, the activation induced by HT7 stimulation was observed on the bilateral postcentral gyrus
, inferior parietal lobule, inferior frontal gyrus
, claustrum, insula, and anterior lobe of the cerebellum, as well as on the left posterior lobe of the cerebellum.
Based on FDG-PET findings, brain metabolism significantly decreased in the orbital gyrus
, cingulate gyrus
, and medial thalamus but increased in the parietal and occipital convexity in Group A compared with that in the control" should be changed to "There were no significant differences in the cognitive tests between Group A and Group B.
However, more recent meta-analyses extended these findings to regions outside the frontal-subcortical areas, including alterations of gray matter density in the superior parietal lobe (Peng et al., 2012; Radua & Mataix-Cols, 2009) supramarginal gyrus
(Rotge et al., 2010), and cerebellum (de Wit et al., 2014).