Each patient underwent clinical evaluation and investigations for screening of DHF diagnosis based on Dengue Expert Advisory Group (DEAG) criteria according to which DHF is characterised by plasma leakage as shown by haemoconcentration
(an increase in Hct >20% above average for age or decrease in Hct >20% of baseline following fluid replacement therapy, pleural effusion, ascites, or hypoproteinaemia.8-11 Repetitive clinical examinations, laboratory investigations, and USG evaluations were conducted in this regard.
Several lines of evidence suggest, however, that the retention of the tourniquet for more than one to two minutes is a significant cause of haemoconcentration
, which may also spuriously increase the concentration of several analytes (36,37), but which can be avoided by using transilluminator devices (38).
as a possible pathogenetic factor of sudden hearing loss.
It is characterized by fever, thrombocytopenia (platelet count less than 100/109/l), petechae, ecchymoses, haemoconcentration
or evidence of plasma leakage.
Cases of DHF also show higher fever, variable hemorrhagic phenomena, thrombocytopenia, and haemoconcentration
. A small proportion of cases lead to dengue shock syndrome (DSS) which has a high mortality rate.
increases blood viscosity and reduces blood flow, especially in the deep veins of the leg in immobile patients, leading to stasis and thus an increased risk of VTE.
may be due to low value of hemoglobin or due to chronic anemia.
Early detection of haemoconcentration
and shock, and their prompt management, rather than platelet transfusions, may be the best measures to decrease the cost, morbidity and mortality associated with dengue fever.
1994; Stout and Crawford 1991), which could lead to thrombosis through haemoconcentration
. On the other hand, we found indications that those with coexisting atrial fibrillation may be particularly vulnerable to the effects of extreme heat.
This presents as the characteristic triad of hypotension, haemoconcentration
and hypoalbuminemia often with an associated monoclonal gammopathy.
 have suggested that protein C may leave the plasma during the period of haemoconcentration
that occurs in acutely cooled subjects.
in cases of diarrhoea was also reported by Smith (1981), Stewart et al.