hemoglobinopathy

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Related to Haemoglobinopathies: hemoglobinopathy

hemoglobinopathy

[‚hē·mə‚glō·bə′näp·ə·thē]
(medicine)
Any blood dyscrasia resulting from the genetically determined alteration of the chemical nature of hemoglobin.
References in periodicals archive ?
[36.] Madigan C, Malik P (2006) Pathophysiology and therapy for haemoglobinopathies. Part I: sickle cell disease.
Testing for haemoglobinopathies in Johannesburg, South Africa: A 30-year review.
In the light of the uncertainty in the influence of anaemia and haemoglobinopathies on HbA1c, it is imperative that clinicians are aware of the caveats with HbA1c values when they make management decisions in the anaemic population.
Gorakshakar et al., "Prevalence of [beta]-thalassemia and other haemoglobinopathies in six cities in India: a multicentre study," Journal of Community Genetics, vol.
However, EMH in the adrenal is uncommon,[sup.2] with less than 10 cases reported.[sup.3] It is thought to be a compensatory, physiological mechanism that occurs during altered medullary haematopoesis which is commonly seen in the haemoglobinopathies, leukemias, lymphomas and myelofibrosis.
Rosatelli, "Prenatal diagnosis and screening of the haemoglobinopathies," Baillieres Clinical Haematology, vol.
Spectrum of haemoglobinopathies in the state of Orissa, India: A ten year cohort study.
His thesis was titled 'Molecular Genetics of Haemoglobinopathies in Oman'.
Guideline: the laboratory diagnosis of haemoglobinopathies. Br J Haematol 1998;101:783-92.
Jaundice in malaria infection is caused by many factors including intravascular haemolysis of parasitized red blood cells, haemolysis of non-parasitized red blood cells (innocent bystanders), possible micro-angiopathic haemolysis associated with disseminated intravascular coagulation (DIC), hepatic dysfunction, associated haemoglobinopathies (not uncommon in malaria-prone areas), druginduced haemolysis (including quinine, etc.), G-6-PD deficiency, etc.
Deficiency or malfunction of these blood cells occurs in disease conditions prevalent in Africa, including cancers like leukaemia and haemoglobinopathies like thalassaemia or sickle-cell disease.