Aetiopathology of Parturient Haemoglobinuria
Babesiosis, caused by Babesia ovis, is one of the most important tick-borne diseases of sheep and goats in Northwest of Iran and is characterized by apathy, fever, anemia, jaundice, and haemoglobinuria
and in some cases mortality may occur.
Luzzatto, "Two distinct patterns of glycosylphosphatidylinositol (GPI) linked protein deficiency in the red cells of patients with paroxysmal nocturnal haemoglobinuria
," The British Journal of Haematology, vol.
Paroxysmal cold haemoglobinuria
(PCH) is a special type of hemolytic syndrome caused by cold agglutinins.
 Hypercoagulation disorders such as systemic lupus erythematosus, antiphospholipid syndrome, the presence of factor V Leiden, paroxysmal nocturnal haemoglobinuria
, hyperhomocysteinaemia, protein C and S deficiency, and heparin-induced thrombocytopenia are also all reported as risk factors for ovarian vein thrombosis.
Lesley Loeliger, from Glasgow, was given 10 years to live after being diagnosed with bone marrow disease paroxysmal nocturnal haemoglobinuria
Flow cytometry may be considered to investigate for an abnormal clone in the case of paroxysmal nocturnal haemoglobinuria
and may be used on bone marrow samples to further evaluate the cells.
A thrombophilia screen for anticardiolipin antibodies, lupus anticoagulant, protein C and S deficiency, factor V Leiden mutation and paroxysmal nocturnal haemoglobinuria
Notable is the occurrence after stem cell transplantation and in the course of aplastic anaemia, paroxysmal nocturnal haemoglobinuria
and the chronic myeloproliferative syndrome neoplasms.
Other signs include repeated generalized convulsions, thrombocytopenia, pulmonary oedema, haemoglobinuria
, splenic enlargement, jaundice and acidosis.
Bone marrow transplantation for paroxysmal nocturnal haemoglobinuria
. Br J Haematol.