Much of the epidemiological and diagnostic effort regarding STEC is directed towards serogroup O157, because of its common association with severe forms of gastrointestinal disease, including haemorrhagic colitis
(HC), and extra-intestinal disease, such as haemolytic uraemic syndrome (1, 2).
VTEC verocytotoxigenic E coli), in particular E cold 0157:H7, have been recognised as a major food borne pathogens, and have caused several large outbreaks of haemorrhagic colitis
in the USA, Japan and the UK.
coli (EHEC) is the main group of verotoxigenic strains which has emerged as the leading cause of haemorrhagic colitis
and haemolytic uremic syndrome (HUS) (2) in humans.
One case had developed ulcerative and haemorrhagic colitis
eighteen months after starting leflunomide treatment and the other case had developed microscopic colitis two years after starting treatment.
An established pathogen, this strain is linked to outbreaks of haemorrhagic colitis
(HC) and haemolytic uraemic syndrome (HUS).
A severe outbreak of haemorrhagic colitis
and haemolytic uraemic syndrome associated with Escherichia coli O157:H7 in Japan.
The symptoms vary from mild diarrhoea to bloody diarrhoea - known as haemorrhagic colitis
- and haemolytic uraemic syndrome (HUS).
Swimming-associated haemorrhagic colitis
due to Escherichia coli O157:H7 infection: Evidence of prolonged contamination of a fresh water lake.
This bacterium was first recognized as a food born pathogen in 1982, when it was associated with two food related outbreaks of haemorrhagic colitis
in the United States (Riley et al.
Symptoms: A serious inflammation of the colon known as haemorrhagic colitis
and haemolytic uraemic syndrome which leads to blood in the urine and can be fatal.
Report from the PHLS Communicable Disease Centre: haemorrhagic colitis
. Br Med J