hemosiderin

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Related to haemosiderin: hemosiderosis

hemosiderin

[‚hē·mō′sid·ə·rən]
(biochemistry)
An iron-containing glycoprotein found in most tissues and especially in liver.
References in periodicals archive ?
This finding may be due to the deposition of haemosiderin laden macrophages in relation to small vessels and bronchioles (15).
Serum ferritin in healthy Danes: relation to marrow haemosiderin iron stores.
Interstitial haemosiderin in the lungs of sudden infant death syndrome: a histological hallmark of 'near-miss' episodes?
The remainder is storage iron ferritin (4-8 mg/kg), haemosiderin (2-4 mg/kg) and iron bound to transferrin (<1 mg/kg).
Two (4%) of these patients had a definite history of trauma but histopathologically did not reveal any extravasated RBC's, fibrin thrombi or haemosiderin laden macrophages.
Cholesterol granuloma (CG) is a histopathologically used term which describes numerous cholestrol clefts that are often surrounded with foreign-body giant cells, foam cells and macrophages filled with haemosiderin.
A low intensity signal on MRI may be found in only few cases all on sequences due to haemosiderin deposits.
For example, ferrous or ferric iron shortens T1 and T2 signal, methaemoglobin causes an increased T1 signal and variable T2 signal whereas haemosiderin decreases T1 and T2 signal.
2) It is suggested that lymphatic and venous obstruction, protein-rich interstitial fluid, tissue haemosiderin and subcutaneous infection contribute to the evolution and perpetuation of chronic lymphoedema.
Iron is also stored in an insoluble form in a poorly defined storage protein, haemosiderin, presumed to be derived from the lysosomal degradation of ferritin.