Summary: TEHRAN (FNA)- Using genetic tools in mice, researchers say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells
, are born in the mammalian inner ear.
Liberman, "Postnatal maturation of auditory-nerve heterogeneity, as seen in spatial gradients of synapse morphology in the inner hair cell
area," Hearing Research, vol.
Although we have shown outer hair cell
damage in our study through SEM, the causes of ototoxicity need to be explained at the molecular level in future studies.
These genes include: Math-1, Myosin, Brn3, EPSIN and AchRa9 which are hair cells
Troiani, "Water-soluble Coenzyme Q10 formulation (Q-ter) promotes outer hair cell
survival in a guinea pig model of noise induced hearing loss (NIHL)," Brain Research, vol.
Type 2 diabetes alters the functional status of outer hair cells
in the cochlea.
Of the transplanted mIESCs in the scala media, 42.6 [+ or -] 5.7% were positive for the hair cell
marker myosin VIIa.
The total number of possible hair cell
bundles did not differ among groups [one-way ANOVA; F(1, 58) = 0.95, P = 0.33].
But new research reveals that supporting cells in the ear can turn into hair cells
in newborn mice.
Selective inner hair cell
loss in premature infants and cochlea pathological patterns from neonatal intensive care unit autopsies.
giant Pfizer is arguably the most advanced of the big players, with a drug in initial Phase I clinical testing trial for age-related sensorineural hearing loss that looks to enhance the function of existing hair cells
The cellular basis for aminoglycoside hearing loss is a destruction of cochlear hair cells
, specifically the outer hair cells