Leukoplakia

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Related to hairy leukoplakia: lichen planus, Kaposi Sarcoma, Oral candidiasis

leukoplakia

[‚lü·kō′plā·kē·ə]
(medicine)
Formation of thickened white patches on mucous membranes, particularly of the mouth and vulva.

Leukoplakia

 

milky-white spots (radius, to 0.5 cm) on the mucous membranes near the skin (for example, on the lower lip) and on the cheeks, tongue, bottom of the mouth, esophagus, cervix uteri, vagina, and urinary bladder.

Leukoplakia is one of the precancerous diseases. Smoking, advanced tooth decay, excessive consumption of alcohol or spices, certain inflammations of the oral cavity, avitaminosis A or B complex, and poorly fitting metal dental bridges, fillings, and crowns may give rise to leukoplakia. The disease occurs in two forms. In simple leukoplakia, the mucous membrane is smooth; its surface resembles mosaic or parquetry. This may be complicated by fissures or erosions. In verrucose leukoplakia, the mucosa is raised and the color varies from pearly to chalky. Patients complain of sensations of petrifaction, burning, and tenderness. Treatment is by surgical removal, electrocoagulation, or radiation therapy.

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These factors were loss of appetite, nausea or vomiting; temperature >38[degrees]C, oral hairy leukoplakia, CD4 count <100 cells/[mm.
Other oral lesions observed in the present study, such as Multifocal Epithelial Hyperplasia, Linear Gingival Erythema, oral ulceration, and Oral Hairy Leukoplakia.
Epstein-Barr virus causes infectious mononucleosis and is associated with several benign and malignant conditions, including Burkitt lymphoma, nasopharyngeal carcinoma, posttransplant lymphoproliferative disorders, Kikuchi histiocytic necrotizing lymphadenitis, hydroa vacciniforme, Gianotti-Crosti syndrome, and oral hairy leukoplakia.
In 1984, Greenspan first published the description of an orallesion that was called hairy leukoplakia, a white lesion on the tongue or mouth floor often characterized by rough projections that look like hairs.
With escalating levels of immunodeficiency, other serious skin diseases such as oral hairy leukoplakia, molluscum contagiosum, eosinophilic folliculitis and resistant herpes simplex are often seen, requiring treatment.
As the CD4 count begins to drop, an infected person may develop thrush, oral hairy leukoplakia, herpes zoster (shingles), or idiopathic thrombocytopenic purpura.
Progression to AIDS in HIV-infected homosexual and bisexual men with hairy leukoplakia and oral candidiasis.
Candida, oral hairy leukoplakia, herpes stomatitis, periodontal and gingival disease, aphthous ulcers and xerostomia are some of the most common manifestations in cases of HIV and AIDS, although initiation of ART has significantly reduced their incidence.
EBV does cause infectious mononucleosis, hairy leukoplakia, and B-lymphoproliferative neoplasms in immunocompromised persons.
Condyloma acuminatum was diagnosed in 11% of attendees during this period, oral hairy leukoplakia in 5.
The recovery of CD4+ cells was accompanied by an absence of any opportunistic infections in the treated group; the untreated subjects experienced persistent oral and vulvovaginal candidiasis, oral hairy leukoplakia and seborrheic dermatitis.