Under the deal, the firms will jointly research and develop a helicase
The human FANCJ helicase
facilitates DNA replication through G4 forming regions and participates in DNA crosslink repair.
Characterization and functional analysis of CReMM, a novel chromodomain helicase
Whereas Roquin destabilizes translationally inactive mRNAs by recruiting the CCR4-NOT deadenylase complex in processing- bodies (PBs) and stress granules (SGs), Regnase-1 localizes to the endoplasmic reticulum (ER) and ribosomes, destabilizes translationally active mRNAs, and requires the RNA helicase
activity of UPF1, similar to NMD.
's technology can provide humans with substantial benefits ranging from better focus to more energy within a matter of weeks, he noted.
Bell et al., "A de novo frame-shift mutation in chromodomain helicase
DNA-binding domain 8 (CHD8): a case report and literature review," American Journal of Medical Genetics Part A, vol.
LGP2 is an RNA helicase
, homologous in structure to RIG-I and MDA5, except that it lacks the 2CARDs that are required to initiate antiviral signaling via the MAVS adaptor protein (Figure 1(c)).
BLAST analysis performed for amino acid sequence of AltMV TGBp1 predicted the existence of N-terminal helicase
In actual the NS3 protein of dengue virus is multifunctional enzyme, acting as protease and a helicase
domain, in specific sites the protease is responsible for the survival of dengue virus.
Nevertheless, the GDS04 strain shares 95.7% aa identity with HKU2 in nonstructural protein (nsp) 3 (adenosine diphosphate-ribose 1'-phosphatase), 96.4% in nsp5 (3C-like protease), 94.6% in nspl2 (RNA-dependent RNA polymerase), 99.8% in nspl3 (helicase
), 99.2% in nspl4 (3'-to-5' exonuclease), 99.4% in nspl5 (poly[U]-specific endoribonuclease), and 97.6% in nspl6 (2'-O-ribose methyltransferase).
encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease.
Peterson, Inhibition of Herpes Simplex Virus Replication by a 2-amino thiazole via Interactions with the Helicase
Component of the UL5-UL8-UL52 Complex.