hemangioendothelioma

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hemangioendothelioma

[hē¦mān·jē·ō‚en·dō‚thē·lē ′ō·mə]
(medicine)
A malignant tumor composed of anoplastic endothelial cells. Also known as hemangiosarcoma.
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Of course, the identification of hemangiomas of infancy (or "HOI" in the trade) was confused with vascular malformations, and no one had recognized variant tumors that were distinct, such as rapidly involuting and noninvoluting congenital hemangiomas (RICHs or NICHs), tufted angiomas, and hemangioendotheliomas.
Many recently reported diagnostic markers are described in this article, such as (1) signal transducer and activator of transcription 6 (STAT6) as the most sensitive and specific IHC marker for solitary fibrous tumor; (2) loss of antihistone H3 acetyl K27 trimethylation (H3K27) nuclear expression in 50% of malignant peripheral nerve sheath tumors, particularly in high-grade malignant peripheral nerve sheath tumors; (3) mucin 4 (MUC4) expression in low-grade fibromyxoid sarcomas and sclerosing epithelioid fibrosarcomas; and (4) nuclear expression of calmodulin binding transcription activator 1 (CAMTA1) in epithelioid hemangioendotheliomas.
Lastly, hemangioendotheliomas have variable histology and may contain necrosis or hemorrhage.
Yoon, "Malignant tumors of blood vessels: angiosarcomas, hemangioendotheliomas, and hemangioperictyomas," Journal of Surgical Oncology, vol.
Treatment for benign liver tumors included prednisolone (4-5mg/kg/day for 28 days) for symptomatic hemangioendotheliomas and surgical resection for mesenchymal hamartomas.
8) Although chondro sarcoma is the most frequent musculoskeletal malignancy encountered in Maffucci syndrome, malignant transformation of skeletal lesions into fibrosarcomas and of vascular lesions into hemangiosarcomas, hemangioendotheliomas, and lymphangiosarcomas have also been reported.
7) Although EHE is generally considered a vascular tumor of intermediate malignancy, it is perhaps better considered as a low-grade form of angiosarcoma given its much more aggressive behavior compared to other hemangioendotheliomas.
Vascular endothelial growth factor receptor-3 (VEGFR-3): a marker of vascular tumors with presumed lymphatic differentiation, including Kaposi's sarcoma, kaposiform and Dabska-type hemangioendotheliomas, and a subset of angiosarcomas.
The majority of consumptive hypothyroidism cases have been described in children with hemangioendotheliomas, but cases have also been reported in adults with massive vascular and fibrous tumors (6-8).
Hemangiosarcomas are malignant neoplasms that arise from the vascular endothelium and are also known as angiosarcomas or hemangioendotheliomas.
Multiple collaterals to hepatic infantile hemangioendotheliomas and arteriovenous malformations: Effect on embolization.
13) In addition, virtually all subtypes of hemangioendotheliomas were positive for ERG, including kaposiform hemangioendotheliomas, retiform hemangioendotheliomas, and epithelioid hemangioendotheliomas.