Myelolipomas are rare benign tumors of mature hematopoietic tissue
and fat and tumorigenic processes are poorly understood.
The pathogenesis of intrathoracic EMH includes the extrusion of bone-marrow stem cells through the thin cortex of the vertebral bodies and ribs, abetted by negative pres-sure; proliferation of the stem cells, which transform into a nodule of hematopoietic tissue
upon demand; and proliferation of the embolized hematopoietic tissues
from other areas to the intrathoracic region, such as the spleen.
Mesodermal derivatives included spindle shaped cells hematopoietic tissue
5C, the hematopoietic tissue
in the low-dose group decreased compared with the normal group, however, the blood sinus were rich as compared to the model group.
The pathological diagnosis was an adrenal ML comprised of mature adipose tissue mixed with hematopoietic tissue
Cr (VI) induced necrosis in tubular epithelium, pycnotic nuclei in the hematopoietic tissue
, narrowing of the tubular lumen and expansion of spaces inside the Bowman's capsule (Ahmad et al.
On the other hand, acute myeloblastic leukemia (AML) is a clonal malignant disease of hematopoietic tissue
Infection with frog virus 3 (FV3), the type species of the genus Ranavirus, results in edema, hemorrhage, and necrosis of lymphoid tissue, hematopoietic tissue
, liver, spleen, and renal tubules (3,5); mortality rates in free-ranging amphibians are >90% (6).
Within the tumor, several foci (red-brown area on gross examination) of mature adipose tissue mixed with hematopoietic tissue
were identified (Figure 3).
When these cells were transplanted into immunocompromised mice, they "formed bone and supported the development of hematopoietic tissue
," the authors wrote.
An important element of our growth strategy involves seeking collaborations with companies looking for a reliable supply of hematopoietic tissue
, including stem/progenitor cells, for their cell-based therapy projects.