hemidesmosome


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Related to hemidesmosome: Adherens junction, Gap junctions

hemidesmosome

[‚hem·ē′dez·mə‚sōm]
(histology)
A structure similar to a desmosome that joins a cell to its basilar membrane rather than to another cell.
References in periodicals archive ?
Hemidesmosome formation, which was observed along the cytoplasmic extensions, and the basal lamina located around the collagen fibres and smooth muscle were demonstrated.
Investigative efforts led to the identification of an immunoglobulin G (IgG) autoantibody, which binds to bullous pemphigoid (BP) antigen 2, also called BP180, which is a protein associated with hemidesmosomes of basal keratinocytes.
IFAP300 is common to desmosomes and hemidesmosomes and is a possible linker of intermediate filaments to the junctions.
We assessed, by electron microscopy, the ability of these antibodies to block laminin-5-induced hemidesmosome assembly in SCC12 cells.
Under electron microscopy, well-formed desmosomes and hemidesmosomes together with pinocytic vesicles, plentiful rough endoplasmic reticulum and 6 nanometer microfilaments are seen (11).
Fingerprint changes are less common and appear as concentric lines due to inadequate formation of hemidesmosomes by the basal epithelial cells and duplication of the epithelial basement membrane.
Other molecules studied by [150] are plakins, which represent a family of molecules which form the links between filaments, desmosomes, and hemidesmosomes and plectin is a cytolinker of this family.
Integrin [alpha]6, extracellular adhesion receptors, is located along the dermal epidermal junction and it means the presence of hemidesmosomes [15].
Sertoli cells were connected to each other by intercellular junctions and they were adherent to the basement membrane by hemidesmosomes.
The presence of keratinized tissue next to an oral implant presents greater benefits than with natural teeth since the keratinized gingiva has more hemidesmosomes and hence provides greater strength to the implant soft tissue interface; also, the submerged implant is less likely to become exposed during the healing process.
Under the zonula occludens and forming an axis in an apical-basal direction are three types of adherence junctions: zonula adherens, also known as belt desmosomes; macula adherens, or punctate desmosomes; and hemidesmosomes.
The peptide compound hexapeptide-10 has been shown to stimulate the formation of laminin-5, alpha6-integrin, and hemidesmosomes, (4) vital building blocks of the dermo-epidermal junction that allow it to reconstruct connectivity between epidermal and dermal cells.