The research investigating the therapeutic effect of HA in patients with hemophilic
arthropathy is rare because bleeding tendency is concerned, and hemophilic
arthropathy is often severe and troublesome.
To the best of our knowledge, IPFP and SPFP volumes have not been characterized in secondary causes of OA, in particular, hemophilic
Karpf et al., "A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic
mice models," Blood, vol.
However, 10-30% of A hemophilic
children develop antibodies against factor VIII as a result of replacement therapy, which give rise to significant difficulties [6,8,20]; in these cases, in accordance with the hematologist, the problem can be solved by administering antihemophilic factor A .
Treatment of an intraoral bleeding in hemophilic
patient with a thermoplastic palatal stent--A novel approach.
Tupin et al., "Role of the intrinsic coagulation pathway in atherogenesis assessed in hemophilic
apolipoprotein E knockout mice," Arteriosclerosis, Thrombosis, and Vascular Biology, vol.
Lundin et al., "The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic
arthropathy," Arthritis and Rheumatism, vol.
Jankiewicz, "Hip arthroplasty in hemophilic
arthropathy," The Journal of Bone & Joint Surgery--American Volume, vol.
Signs and symptoms can vary from intracranial Hemorrhage to easy bruising, intramuscular hematomas and hemarthrosis begin when child "Begins to cruise." Although hallmark of hemophilic
bleeding is hemarthrosis, the earliest joint hemorrhage appears most commonly in the ankle.
In the state of Mato Grosso do Sul the first AIDS case was identified in 1984 in a hemophilic
child and the first adult case was identified in 1985.
Contrary to the results of the present study another study on the prevalence of viral hepatitis in Zahedan was carried out on hemophilic
patients in the Zahedan Hemophilia Center and demonstrated a prevalence of 4.9% and 29.6% for HBsAg and HCVAb respectively.13 Similar previous studies13,14 have also reported mostly higher prevalence rates than ours in thalassemic patients (0.3% for HBsAg and 13.5% and 14.4% for HCVAb), blood donors (16% for HBsAg), pregnant women (6.5% for HBsAg) or barbers (31.4% for HBsAg) in Zahedan.