Hemotoxins

(redirected from hemotoxin)
Also found in: Dictionary, Medical, Wikipedia.

Hemotoxins

 

substances of plant, animal, or microbial origin that injure the membranes of red blood cells and cause them to undergo hemolysis. Hemotoxins are mainly enzymes like lecithinases or phospholipases, which split phospholipids in the membranes of red blood cells, or saponin-like substances that act on another component of the membrane, cholesterol. Hemotoxins may be of microbial origin (from staphylococci, streptococci, and so forth), plant origin (tox-albumins, ricin, crotin, saponin, and abrin), or animal origin. The latter include arachnolysins of certain spiders (such as Latrodectus, Atrax, and Lycosa), hemotoxins of parasitic worms (Dibothriocephalus), and snake venoms, especially those of snakes from the families Viperidae and Crotalidae. The red blood cells of different animal species vary in sensitivity to the same hemotoxin. For example, snake venoms (like cobra venom) lyse the red blood cells of guinea pigs, dogs, and man but not those of cattle, sheep, and goats. Lecithins and cholesterol in large doses block the action of hemotoxins.

KH. KH. PLANEL’ES

Mentioned in ?
References in periodicals archive ?
Venoms of true vipers (Viperinae) and of pit vipers (Crotalinae) contain hemotoxins, e.
Topical treatment isn't enough--you've gotta get the neuro-, necro-, and hemotoxins out
The venom of these species, which contains powerful cytotoxins, necrotoxins and hemotoxins (Gertsch 1967), together with the tendency of many species to form large populations in urban areas, close to human constructions, has made these spiders a public health problem in Chile (Schenone et al.