heparin


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heparin

(hĕp`ərĭn), anticoagulantanticoagulant
, any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other
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 produced by cells in many animals. A polysaccharide, heparin is found in the human body and occurs in greatest concentration in the tissues surrounding the capillaries of the lungs and the liver. The substance, extracted from animal tissues, is used clinically to delay blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
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heparin

[′hep·ə·rən]
(biochemistry)
An acid mucopolysaccharide acting as an antithrombin, antithromboplastin, and antiplatelet factor to prolong the clotting time of whole blood; occurs in a variety of tissues, most abundantly in liver.
References in periodicals archive ?
Browse 44 Market Data Tables and 39 Figures spread through 218 Pages and in-depth TOC on "Low Molecular Weight Heparin Market, by Drug (Enoxaparin, Dalteparin, Nadroparin, Bemiparin, Tinzaparin, and Others), by Packaging (Multi-vials and Prefilled Syringes), by Application (Deep Vein Thrombosis, Acute Coronary Syndrome (ACS), Pulmonary Embolism, and Atrial Fibrillation), by End Use (Hospitals (Private and Public), Clinics, and Home), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Global Forecast to 2026"
Therefore much attention is needed regarding subcutaneous injection of low-molecular-weight heparin for elderly patients.
Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease.
Heparin has been used in nanoparticle synthesis procedures since some time ago.
Another heparin interacting protein is factor 4 (CXCL4-PF4) which is released from activated platelets during platelet aggregation and promotes blood coagulation [44].
For the 12 months ending 31 October 2017, US sales for the company's Heparin Sodium Injection USP, 1,000 USP/ml, 5,000 USP/ml, 10,000 USP/ml and 20,000 USP/ml were about USD185m, according to IQVIA.
The patient also had received ketamine and pancuronium bromide injection just before the heparin, making the allergy diagnosis difficult.
Yong Xu said that in addition to its role as an anticoagulant, heparin is normally produced by the body, has been known to affect other biological functions.
These results, combined with studies demonstrating fewer bleeding complications and non-fatal myocardial infarction, and reduced 30-day mortality of high-risk ACS patients, further support the use of Anti-Xa testing to accurately monitor heparin therapy.
Under a supply agreement entered into in 2001, Scientific Protein Laboratories LLC ("SPL") supplied heparin products to Wyeth Pharmaceuticals, Inc.
Notably, no heparin was given, no blood reinfusion or salvage devices were used, and no central venous or arterial catheters were used intraoperatively.