heparin

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heparin

(hĕp`ərĭn), anticoagulantanticoagulant
, any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other
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 produced by cells in many animals. A polysaccharide, heparin is found in the human body and occurs in greatest concentration in the tissues surrounding the capillaries of the lungs and the liver. The substance, extracted from animal tissues, is used clinically to delay blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/

heparin

[′hep·ə·rən]
(biochemistry)
An acid mucopolysaccharide acting as an antithrombin, antithromboplastin, and antiplatelet factor to prolong the clotting time of whole blood; occurs in a variety of tissues, most abundantly in liver.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The company said the Heparin Sodium Injection USP, 1,000 USP/ml, 5,000 USP/ml, 10,000 USP/ml and 20,000 USP/ml are packaged in multi-dose vials.
Our results suggest that adding heparin sodium to the irrigating solution seems to be a safe, effective, and promising method to prevent early postoperative inflammatory reactions in hihg risk cataract surgery.
The Heparin Sodium USP had also been supplied to SBPC by another producer, Qingdao Kangyuan, from approximately 2001 until 2006, without informing the FDA.
Recall--Firm press release: Baxter to proceed with recall of remaining heparin sodium vial products.
In ASSENT 3, patients presenting within six hours of symptom onset will be randomized into three parallel treatment groups receiving varying doses of TNKase with heparin sodium (Group A), with enoxaparin sodium (Group B), or with the anti-platelet agent ReoPro(TM) (abciximab), manufactured by Centocor Pharmaceuticals, and heparin sodium (Group C).
Heparin sodium versus 0.9% sodium chloride injection for maintaining patency of indwelling intermittent infusion devices.
1250 anti-Xa Units of Org 101 72 once daily is both safe and as effective as 5000 IU of heparin sodium twice daily given for DVT prophylaxis in patients with acute ischaemic stroke of recent onset.
With this most recent offering we're also proud to offer the most comprehensive portfolio of Heparin Sodium in the U.S."
VR496 is Vectura's proprietary formulation of dry powder heparin sodium and has been designated orphan drug status by the European Medicines Agency (EMA) and Food and Drug Administration (FDA).
Anticoagulant Comparison Heparin Sodium Enoxaparin Warfarin Sodium Use * DVT prophylaxis * DVT prophylaxis.
UNFRACTIONATED HEPARIN Drug Dosage Cost/Day [*] heparin sodium bolus dose of 75 U/kg of $5.98 (1,250 body weight; initial U/hr) maintenance dose of 1,250 U/hr Drug Comment [+] heparin sodium Unfractionated heparin has a much longer track record for treating unstable angina than both LMWHs combined, and its biologic potency is similar to that of the LMWHs.

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