Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma
in cirrhotic patients.
In contrast, HCV progression to HCC rarely occurs in noncirrhotic patients." It was important to explore projected trends in etiology of hepatocellular carcinoma
to inform the development of screening, diagnostic, and treatment approaches, particularly given potential differences in the pathology, natural history, and treatment options for NASH-related and HCV-related liver cancer.
(HCC) is a complex condition with multiple variables affecting the disease course and response to treatment, including liver function and performance status of the patient and tumour stage.
Treatment with DAAs reduced risk of hepatocellular carcinoma
when compared with no DAA treatment, with a hazard ratio of 0.66 (95% confidence interval, C 46-0.93), and reduced risk of all-cause nortality, with an HR of 0.48 (95% CI, 0.33-0.70), investigators reported in a multivariable analysis that adjusted for variables including age, sex, fibrosis score, HCV genotype, alcohol use, and more.
In addition to ongoing clinical studies of the LENVIMA and KEYTRUDA combination, the companies will jointly initiate new clinical studies through the LEAP (LEnvatinib And Pembrolizumab) clinical program, which will evaluate the combination to support 11 potential indications in six types of cancer (bladder cancer, endometrial cancer, head and neck cancer, hepatocellular carcinoma
, melanoma and non-small cell lung cancer).
Amulti-institutional phase II trial of hepatic arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma
with portal vein tumor thrombosis.
Clinico-pathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma
with and without cirrhosis.
Molecular pathogenesis of hepatocellular carcinoma
and impact of therapeutic advances.
Hepatitis C virus to hepatocellular carcinoma
. Infect Agent Cancer.
"Among patients with previously treated advanced hepatocellular carcinoma
, treatment with cabozantinib resulted in longer overall survival and progression-free survival than placebo," the authors write.
Ahn et al., "Resection of metachronous adrenal metastasis after liver resection and transplantation for hepatocellular carcinoma
," Digestive Surgery, vol.