It is important to confirm whether miR-155 can regulate TNF production during
hepatocyte apoptosis in vitro.
The surface structure of section of liver of control rabbits showed normal
hepatocyte cords and regular polyhyderal structure of hepatocyt (Fig.
In males, A) immunoreactivity of 4-HNE was observed mainly in the cytoplasm of
hepatocytes around central vein of hepatic lobules in the control group (arrow), B) 4-HNE was strongly expressed in the cytoplasm of most
hepatocyte of hepatic lobule in the cyclohexanone-exposed group (arrow).
Molecular profiling data described above indicate that the HepaRG cell line in many ways resembles human primary
hepatocytes, which is encouraging for utilization of these cells in the studies of xenobiotic metabolism, hepatotoxicology, and
hepatocyte differentiation.
This approach closely mimics the function of a human liver and allows the
hepatocytes to maintain normal metabolic activity for several weeks.
The review summarises the effects of liver temperature, hepatic perfusion, and canalicular transporter deficiency on Gd-BOPTA
hepatocyte concentrations.
Systemizing a New Concept: Domino
Hepatocyte Transplantation (DHT).
Next, the medium was changed to RPMI/B27 supplemented with 20 ng/mL
hepatocyte growth factor (HGF, PeproTech) for an additional 5 days in hypoxia.
The [BrdU.sup.+] hepatocyte/ total
hepatocyte ratio was calculated (Figure 2(c)).
Akaike et al., "Preparation of alginate/galactosylated chitosan scaffold for
hepatocyte attachment," Biomaterials, vol.
Hemodynamic flow is well documented to improve rat
hepatocyte morphology, function, and metabolic activity in vitro [17-19].
Although gp130 is present in almost all cells, IL-6R is only expressed in limited cell types, for example,
hepatocyte; thus, it seems that the effect of IL-6 is restricted to these cells.