We determined that serum Creatinine levels & blood urea levels in patients with the hepatorenal syndrome
was significantly higher than that of other different groups (p<0.05) but there was no significant change in creatinine levels between patients with compensated cirrhosis and control group.
Our study also established that severe hyponatraemia was associated with worsening jaundice, portal hypertension, higher grades of encephalopathy, increasing incidence of hepatorenal syndrome
and spontaneous bacterial peritonitis.
Conclusion: T allele located at arginine vasopressin receptor 1a receptor promoter rs113481894 locus may be associated with the pathogenesis of type I hepatorenal syndrome
TIPS can improve refractory ascites, variceal bleeding, refractory hepatic pleural effusion, hepatorenal syndrome
, refractory ascites, and variceal hemorrhage, which are the appropriate indications.
It lacks the assessment of correlation of hyponatremia with complications of decompensated cirrhosis like refractory ascites, spontaneous bacterial peritonitis, encephalopathy, variceal heamorrage and hepatorenal syndrome
. It also does not throw light on the effect of sodium replacement in the management of these complications including their prevention.
Myeloablative allogeneic hematopoietic cell transplantation could be complicated by hepatorenal syndrome
TIPS significantly improves LFT survival, liver disease related death, recurrence of ascites and Hepatorenal syndrome
but it also increases the risk of post TIPS hepatic encephalopathy in 30% of cases.
KEY WORDS: Cirrhosis, Hepatorenal syndrome
(HRS), intravenous albumin, Terlipressin.
Patients with NASH cirrhosis, like those with cirrhosis of other etiologies, are at risk for complications, including hepatic encephalopathy, ascites, hepatorenal syndrome
, and esophageal variceal hemorrhage.
group B: 4:4, p= non-significant (NS)) and hepatorenal syndrome
(group A vs.
(HRS) is a distinct form of functional kidney injury seen in end-stage liver disease.