hepatotoxin

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hepatotoxin

[¦hep·əd·ō′täk·sən]
(pharmacology)
An agent capable of damaging the liver.
References in periodicals archive ?
1: IVIVE potential for hepatotoxic endpoints Categories * Number of InVitro_ compounds Rat-InVivo All compounds 120 0.
This study was carried out to see the hepatotoxic effect and reversibility of changes on gross, biochemical and histological basis.
Several PAs have been found to cause hepatotoxic, mutagenic and cancerogenic effects--accounting for the toxicological relevance of PAs to humans (Chen et al.
The spores of Pithomyces chartarum fungus can contain the hepatotoxic sporidesmin that can cause hepatogenous photosensitization like Brachiaria poisoning.
Before prescribing potentially hepatotoxic medications, order baseline liver function tests.
Effect of corosolic acid on the activities of mitochondrial tricarboxylic acid cycle enzymes in CCl4- hepatotoxic rats
Comparative studies on histopathological hepatotoxic effects of antituberculardrugs (rifampicin and isoniazid) in Mus musculus.
It is also quite likely that uninterrupted administration of hepatotoxic drugs (dapsone and rifampicin) during the entire period of chronic ENL led to further deterioration of hepatic function and eventually to the development of a superimposed pustulonecrotic, acute ENL over and above the chronic ENL, which was instrumental in precipitating the fulminant hepatic failure.
Although silymarin is hepatoprotective in animal experiments and some human hepatotoxic exposures, its efficacy in ameliorating the symptoms of acute clinical hepatitis remains inconclusive.
The participants were not taking hepatotoxic medications, and there was no uncertainty as to the skin examination findings.
To complicate matters, the HIV/TB co-infected patient is often exposed to other potentially hepatotoxic drugs and is prone to conditions associated with liver injury.
Its toxicity is attributed to the presence of a hepatotoxic terpenoid known as atractyloside, a powerful inhibitor of cellular respiration and ATP synthesis.