hepatotoxin

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hepatotoxin

[¦hep·əd·ō′täk·sən]
(pharmacology)
An agent capable of damaging the liver.
References in periodicals archive ?
1: IVIVE potential for hepatotoxic endpoints Categories * Number of InVitro_ compounds Rat-InVivo All compounds 120 0.
In vitro to in vivo extrapolation for drug-induced liver injury using a pair ranking method
This study was carried out to see the hepatotoxic effect and reversibility of changes on gross, biochemical and histological basis.
HEPATOTOXIC EFFECT OF NICKEL SULPHATE ON MICE
Several PAs have been found to cause hepatotoxic, mutagenic and cancerogenic effects--accounting for the toxicological relevance of PAs to humans (Chen et al.
Detection of pyrrolizidine alkaloids in German licensed herbal medicinal teas
The spores of Pithomyces chartarum fungus can contain the hepatotoxic sporidesmin that can cause hepatogenous photosensitization like Brachiaria poisoning.
The effect of ensiling and haymaking on the concentrations of steroidal saponin in two Brachiaria grass species/O efeito da ensilagem e fenacao sobre as concentracoes de saponina esteroide em duas especies de graminea Brachiaria
Before prescribing potentially hepatotoxic medications, order baseline liver function tests.
How to modify psychotropic therapy for patients who have liver dysfunction
Effect of corosolic acid on the activities of mitochondrial tricarboxylic acid cycle enzymes in CCl4- hepatotoxic rats
EFFICACY OF COROSOLIC ACID ON MITOCHONDRIAL ENZYMES AND DNA DAMAGE AGAINST CCL4-INDUCED HEPATOTOXIC RATS
Comparative studies on histopathological hepatotoxic effects of antituberculardrugs (rifampicin and isoniazid) in Mus musculus.
Rifampicin Induced Embryotoxicity in Mus musculus
It is also quite likely that uninterrupted administration of hepatotoxic drugs (dapsone and rifampicin) during the entire period of chronic ENL led to further deterioration of hepatic function and eventually to the development of a superimposed pustulonecrotic, acute ENL over and above the chronic ENL, which was instrumental in precipitating the fulminant hepatic failure.
Fulminant hepatic failure in a 15 year old boy with borderline lepromatous leprosy and Type 2 reaction
Although silymarin is hepatoprotective in animal experiments and some human hepatotoxic exposures, its efficacy in ameliorating the symptoms of acute clinical hepatitis remains inconclusive.
Milk thistle
The participants were not taking hepatotoxic medications, and there was no uncertainty as to the skin examination findings.
Psoriasis linked to nonalcoholic fatty liver disease
To complicate matters, the HIV/TB co-infected patient is often exposed to other potentially hepatotoxic drugs and is prone to conditions associated with liver injury.
Consensus statement: management of drug-induced liver injury in HIV-positive patients treated for TB
Its toxicity is attributed to the presence of a hepatotoxic terpenoid known as atractyloside, a powerful inhibitor of cellular respiration and ATP synthesis.
Intoxicacion accidental de un toro con Wedelia glauca ("sunchillo") confirmada por analisis de contenido ruminal
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