hepatomegaly

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hepatomegaly

[‚hep·əd·ō′meg·ə·lē]
(medicine)
Enlargement of the liver.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The aim of current study was to determine the development of cisplatin induced oxidative stress followed by evaluation of hepatotoxicity in laboratory animals.
L's unremarkable valproic acid levels combined with the psychiatry assessment ruled out valproic hepatotoxicity due to overdose, either intentional or accidental.
Involvement of oxidative stress is the major mechanism of CBZ induced hepatotoxicity. Several antioxidant treatments have been reported to reduce the hepatotoxicity of CBZ (Maheswari et al., 2015a, b).
Two patients and one patient developed hepatotoxicity in the 2-month regimen and 3-month regimen groups, respectively (10.5% vs.
Cyclophosphamide, a chemotherapeutic agent, has side effects, especially hepatotoxicity. Currently, NC, which has antioxidant properties, is an appropriate candidate for the reduction of oxidative stress due to medicines (17).
Our results showed that PZA-induced hepatotoxicity represents a state of increased oxidative stress, which is interfered with the evidence of motivating ROS generation in rat's liver.
4) Age: age can determine the biochemical expression of hepatotoxicity. Elderly patients have a strong relationship with cholestatic or mixed liver injury.
Hepatotoxicity is more frequently discovered during postmarketing studies or, even, much later.
Hiatt, "Acetaminophen hepatotoxicity and acute liver failure," Journal of Clinical Gastroenterology, vol.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are the drugs most commonly implicated in hepatotoxicity. The two most commonly used NNRTIs Nevirapine and Efavirenz are frequently used as part of the triple combination first-line ART regimen [5].
Rifampin increases hydrazine by induction of isoniazid hydrolase, which may explain the severe hepatotoxicity [29].
Till now, the association of IL-1RN (VNTR) and IL-1[beta] (-511C/T) polymorphisms has not been described with the severe hepatotoxicity and its prevalence in HIV-infected individuals on NNRTI-containing ART and healthy controls.