is often the initial presentation during the first ("Primary") herpes simplex infection.
These cases comprise primary herpetic gingivostomatitis
or the well-known orolabial HSV To characterize the more atypical presentations in the pediatric population, the investigators reviewed the charts of all 48 patients referred to their pediatric dermatology clinic in a 10-year period after receiving a diagnosis of HSV Only 19% of these patients were older than 11 years of age, and more than 40% were younger than 2 years of age at presentation.
[24.] Blevins JY.--Primary herpetic gingivostomatitis
in young children.
In primary herpetic gingivostomatitis
, is characterized by multiple ulcers.
Infective included the bacterial, fungal and viral diseases; such as primary herpetic gingivostomatitis
, herpes zoster, herpangina, infectious mononucleosis, acute necrotizing ulcerative gingivitis, tuberculosis, syphilis, actinomycosis and HIV infection.
HSV-1 is a highly prevalent pathogen causing primary infections which present clinically as herpes labialis or as primary herpetic gingivostomatitis
. About 12% of primary HSV-1 infections are associated with symptoms, e.g.
kingae bacteremia was documented in 4 (13.7%) of 29 young children with culture-proven herpetic gingivostomatitis
, confirming the role played by viral infections in the pathogenesis of infections caused by the organism (9).