Mammalian nAChRs contain five subunits divided into the alpha ([alpha]2-[alpha]7, [alpha]9, and [alpha]10) and beta ([beta]2-[beta]4) subfamilies, which assemble into both heteromeric
and homomeric pentamers .
IL-33 signals via a heteromeric
receptor that consists of ST2L (or ST2) and IL-1R accessory protein (IL-1RAcP) .
Cutting edge: interleukin 17 signals through a heteromeric
TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric
NMDA receptors: Molecular and functional distinction of subtypes.
Histone methyltransferases g9a and glp form heteromeric
complexes and are both crucial for methylation of euchromatin at h3-k9.
Smith, "A heteromeric
protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity," Genes and Development, vol.
If part of the heteromeric
complex is activated, it will manipulate the receptor binding properties of the same complex .
PII can regulate ACCase activity by interacting with BCCP subunits of heteromeric
HtACCase (Feria Bourrellier et al., 2010), which was regulated by WRI1 (Baud et al., 2010).
In addition, SPP1 can bind to heteromeric
integrin [alpha]v[beta]6 (Erikson et al.
These receptors are heteromeric
protein complexes composed of multiple subunits that are arranged to form ligand-gated ion channels.
"We believe the table provides a useful visual tool for connecting heteromeric
topologies to each other and to their homomeric equivalents," Ahnert said.