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HIE(Health Information Exchange) A service that enables exchange of healthcare information between hospitals and regions. The information is not only used to provide medical data for people who move to a different geographic area, but also to provide statistics for public health in general. There are many regional health information organizations (RHIOs) throughout the U.S. that are involved in health information exchange (HIE), and the terms RHIO and HIE are used synonymously. See NHIN and healthcare IT.