Members of the
homeobox gene family are among the important factors involved in craniofacial development.
The rough sheath2 gene negatively regulates
homeobox gene expression during maize leaf development.
Oftalmik gelisimde onemli olan iki
homeobox gen ailesi, PAX ve HOX gen aileleridir.
Upregulation of the cardiac
homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload.
A number of schizencephaly patients including 2 brothers are heterozygous for germline mutations in the
homeobox gene EMX2.
Two other possible mechanisms are a deficiency in retinoic acid and altered expression of
homeobox genes.
Having identified the
homeobox segment, researchers searched for it in other organisms.
[1990]: '
Homeobox Genes and the Vertebrate Body Plan', Scientific American, 263, July, pp.
A
homeobox is a region of a gene that enables it to control other genes crucial to a plant's final form and function.
[4.] Dunwell TL, Holland PW Diversity of human and mouse
homeobox gene expression in development and adult tissues.
In this regard, the differentiation of the genital tubercle after the initiation of Shh signaling from the urethral epithelium leads to the upregulation of bone morphogenetic protein 4 (Bmp4),
homeobox protein a13 (Hoxa13), Hoxd13, and Shh receptor, Patc, gene expression.
La diferenciacion de las celulas intersticiales (de Leydig) es regulada por el morfogeno Desert Hedgehog (DHH), secretado por las celulas sustentaculares (Pierucci-Alves et al., 2001), aunque tambien estan involucrados el factor de crecimiento derivado de plaquetas (PDGFA) y el gen
Homeobox Arx (Griswold & Behringer).
