homeobox


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homeobox

[′hō·mē·ə‚bäks]
(cell and molecular biology)
A highly conserved sequence of deoxyribonucleic acid (DNA) that occurs in the coding region of development-controlling regulatory genes and codes for a protein domain that is similar in structure to certain DNA-binding proteins and is thought to be involved in the control of gene expression during morphogenesis and development.
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References in periodicals archive ?
Members of the homeobox gene family are among the important factors involved in craniofacial development.
The rough sheath2 gene negatively regulates homeobox gene expression during maize leaf development.
Oftalmik gelisimde onemli olan iki homeobox gen ailesi, PAX ve HOX gen aileleridir.
A number of schizencephaly patients including 2 brothers are heterozygous for germline mutations in the homeobox gene EMX2.
Two other possible mechanisms are a deficiency in retinoic acid and altered expression of homeobox genes.
Having identified the homeobox segment, researchers searched for it in other organisms.
[1990]: 'Homeobox Genes and the Vertebrate Body Plan', Scientific American, 263, July, pp.
A homeobox is a region of a gene that enables it to control other genes crucial to a plant's final form and function.
[4.] Dunwell TL, Holland PW Diversity of human and mouse homeobox gene expression in development and adult tissues.
In this regard, the differentiation of the genital tubercle after the initiation of Shh signaling from the urethral epithelium leads to the upregulation of bone morphogenetic protein 4 (Bmp4), homeobox protein a13 (Hoxa13), Hoxd13, and Shh receptor, Patc, gene expression.
La diferenciacion de las celulas intersticiales (de Leydig) es regulada por el morfogeno Desert Hedgehog (DHH), secretado por las celulas sustentaculares (Pierucci-Alves et al., 2001), aunque tambien estan involucrados el factor de crecimiento derivado de plaquetas (PDGFA) y el gen Homeobox Arx (Griswold & Behringer).