Conclusion: Systolic blood pressure and duration of diabetes showed a significant positive correlation with homocysteine
. The correlation of homocysteine
with HbA1c was not certain from researcher's point of view and further studies of larger sample size and longer duration must be conducted to ascertain the association between the two variables.
The link between Alzheimer's and homocysteine
is not speculative, either; on the contrary, what has been dubbed "the homocysteine
hypothesis" is based upon the observation that Alzheimer's patients have significantly elevated serum concentrations of homocysteine
The comparison of homocysteine
level between healthy controls and PXS patient s showed a highly significant (p-value<0.01) difference between both groups.
* High total plasma homocysteine
is strongly associated with age-related hearing loss.
Data regarding association of homocysteine
and subclinical hypothyroidism is very limited in North-East India.
Subsequently, plasma serum homocysteine
, glucose, total lipid profile concentration, ESR, forearm blood flow, and vascular resistance were determined.
Furthermore, in the research conducted on PD patients, homocysteine
level of cerebrospinal fluid has been reported higher than normal .
is a sulfur-containing amino acid that is derived from the metabolism of methionine (Met), which is rapidly oxidized in plasma to the disulfides homocysteine
and cysteine-homocysteine.[sup] Met can be converted to S-adenosylmethionine (SAM), which is catalyzed by methionine adenosyltransferase.
High levels of homocysteine
have been shown to increase the risk of (http://circ.ahajournals.org/content/111/19/e289) hardening of the arteries (atherosclerosis), which could eventually result in a heart attack and/or stroke, and (http://www.fvleiden.org/ask/77.html) blood clots in the veins , referred to as venous thrombosis.
Methionine and homocysteine
are two very important amino acids.
theory" of atherosclerosis came up from the observation that diseases such as homozygous homocystinuria, which are characterized by severe hyperhomocysteinemia are associated with premature vascular disease.