homozygote

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homozygote

(hō'mōzī`gōt): see geneticsgenetics,
scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation to generation in 1856, it was not until the discovery and detailed study of the
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Homozygote

 

a cell or an organism in whose genetic makeup the homologous chromosomes carry the identical form of a given gene. A homozygote originates during the fusion of gametes that are identical for a given gene. The genetic formula of a diploid organism homozygous for allele A or a can be written in the form AA or aa; for a triploid organism, AAA or aaa; and so forth.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

homozygote

[¦hō·mə′zī‚gōt]
(genetics)
An individual who has identical alleles at one or more loci and therefore produces identical gametes with respect to these loci.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
These analyses revealed that simultaneously maternal homozygosity in 1G/1G MMP1 and 5A/5A MMP3 increases the risk of pre-eclampsia development over 10-fold (OR =10.22, 95% CI 2.28-45.8; p < 0.01).
Homozygosity at CRB1 locus (1q31.1) with four amplified markers (D1S2816, D1S2840, D1S2816 and D1S1660) shown a clear homozygous pattern for all affected and heterozygous against controlled members which confirmed it as a diseased locus.
Comparison of homozygous samples by NGS and an alternate method demonstrated a high degree of concordance and confirmation of homozygosity. In addition, when evaluating 1893 samples for homozygosity, CHOP found 2 cases of false homozygous typing by NGS when compared with an alternate method, one each for HLA-DRB1 and DQB1.
Sequence analysis carried out in an affected SA boy from a consanguineous Venda family revealed homozygosity for a single nucleotide insertion in exon 5, which resulted in a frame shift and premature stop codon p.(Gly278Argfs*95).
Genome-wide homozygosity mapping analysis of samples derived from three affected individuals (IV-3, IV-6, and IV-7) identified 6 different disease-associated loci (Table 2 and Figure 1(c)).
Although sequencing analysis cannot exclude a large heterozygous deletion in the CYP11B2 gene in trans to c.1398+2T>A (i.e., hemizygosity), homozygosity of c.1398+2T>A is most likely.
Green, "Polycythaemia associated with homozygosity for the abnormal haemoglobin Sherwood Forest ([beta]104(G6) Arg [right arrow] Thr)," British Journal of Haematology, vol.
Genome-wide homozygosity mapping on four family members (unaffected parents and the two affected siblings) was performed using 300K single-nucleotide polymorphism (SNP) microarray (HumanCytoSNP12.2 chip) along with iScan platform (Illumina, USA).
Among their topics are allopolyploidy and interspecific hybridization for wheat improvement, polyploidy in maize: the impact of homozygosity and hybridity on phenotype, broadening the genetic basis for crop improvement: interspecific hybridization within and between ploidy levels in Helianthus, oat improvement and innovation using wild genetic resources (Poaceas, Avena spp.): elevating "oats" to a new level and stature, and interspecific hybridization for chickpea (Cicer arietinum L.) ([umlaut] Ringgold, Inc., Portland, OR)
Until now, there are few reports showing homozygosity for Robertsonian translocations which are summarized in table 1.