human leukocyte antigen


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human leukocyte antigen

[¦yü·mən ¦lü·kə‚sīt ′ant·i·jən]
(immunology)
Any of a group of antigens present on the surface of nucleated body cells that are coded for by the major histocompatibility complex of humans and thus allow the immune system to distinguish self and nonself. Abbreviated HLA.
References in periodicals archive ?
Nguyen, "Human leukocyte antigen class I epitopes: update to 103 total epitopes, including the C locus," Transplantation, vol.
Associations between human leukocyte antigen type and nasopharyngeal carcinoma in Caucasians in the United States.
Table 1--Frequency of human leukocyte antigens (HLA) associated with rapid progression to AIDS in Brazilian AIDS patients presenting with: (i) toxoplasmic encephalitis (Group 1); (ii) antibody against T.
These include provision of human leukocyte antigen (HLA)-matched platelets or HLA "compatible" (antigen-negative) platelets, platelets selected by cross-matched tests, and maneuvers to reduce alloimmunization.
Human leukocyte antigens and susceptibility to tuberculosis: a meta-analysis of case-control studies.
The Food and Drug Administration is investigating preliminary data indicating that people with the human leukocyte antigen (HLA) allele HLA-B*1052 may be at greater risk of developing Stevens-Johnson syndrome and toxic epidermal necrolysis if they receive phenytoin or fosphenytoin.
The 31 contributions collected describe immunoinformatic databases and their applications for search and mapping of immune system responses, defining and classifying human leukocyte antigen supertypes, predicting peptide-major histocompatibility complex binding, and predicting other properties of immune systems.
In the 1970s, scientists found that a specific version of a gene encoding human leukocyte antigen DRB1, an immune system protein, conferred a fourfold increase in the risk of MS.
In 2002, QIAGEN purchased GenoVision (see IBO 5/31/02), a provider of magnetic bead-based nucleic acid purification technology used in HLA-typing (Human Leukocyte Antigen) for transplantation diagnostics.
Human leukocyte antigen may be involved in the chronicity of hepatitis B virus (HBV) infection.
Researchers found that both children and adults with lichen sclerosus have human leukocyte antigen class II DQ7, suggesting the disease is the same and may persist into adulthood.

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