human leukocyte antigen


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Related to human leukocyte antigen: major histocompatibility complex, Human Leukocyte Antigen B27

human leukocyte antigen

[¦yü·mən ¦lü·kə‚sīt ′ant·i·jən]
(immunology)
Any of a group of antigens present on the surface of nucleated body cells that are coded for by the major histocompatibility complex of humans and thus allow the immune system to distinguish self and nonself. Abbreviated HLA.
References in periodicals archive ?
YT Chen has discovered that patients who possess the human leukocyte antigen (HLA) alleles, HLA-B*5801 or HLA-B*1502, have a hundred to a thousand fold higher risk of developing SJS or TENS when given certain drugs.
A woman's father--or at least his human leukocyte antigen (HLA) type--has a lot of influence on whether she likes a man's body odor, University of Chicago researchers report.
McDevitt of the Stanford University School of Medicine performed detailed analysis of human leukocyte antigen (HLA) molecules in 39 diabetic patients and compared them to normal controls.
A study published this month in the journal Tissue Antigens reports that researchers at Roche Molecular Systems (SWX:RO) (SWX:ROG) (Pink Sheets: RHHBY) in Pleasanton, CA have used high-throughput sequencing technology from 454 Life Sciences, a Roche Company, to carry out high-resolution human leukocyte antigen (HLA) genotyping in research samples.
The team focused on different DNA variations of HIV in conjunction with different forms of human leukocyte antigen (HLA), a group of molecules that orchestrate immune response.
With a thrill akin to that accompanying the first live pictures from the moon, scientists are gazing upon the first three-dimensional pictures of a human leukocyte antigen, or HLA--the mysterious molecular complex that is essential to the body's killer-cell immune response.
Invitrogen, a division of Life Technologies Corporation (NASDAQ:LIFE), today announced that its DynaChip([R]) HLA Antibody Analysis System has received approval from Health Canada's Medical Device Bureau for the detection and identification of antibodies to human leukocyte antigen (HLA) markers, which is an essential step in determining the compatibility of organ donors.
CLSI has also published a new document, Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Approved Guideline (I/LA29-A), which describes criteria for optimizing flow cytometry crossmatching and the detection of human leukocyte antigen (HLA) alloantibody by solid-phase methods in conventional and multiplex platforms.
The human leukocyte antigen system (HLA) is a major component of the immune system in humans and is fairly unique from person to person.
The DynaChip[TM] system is the only automated chip-based system for human leukocyte antigen (HLA) antibody detection and identification.
The current and emerging technologies for detecting and characterizing human leukocyte antigen (HLA) alloantibodies provide powerful tools for predicting the risk of immunological response to a transplant.
Apthera has patents and strong proprietary protection on the naturally presented human leukocyte antigen (HLA) peptides, methods of use, compositions, modifications, and processes.

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