human myeloma protein

[‚hyü·mən ‚mī·ə‚lō·mə ′prō‚tēn]

(immunology)

Any of a group of the first structurally discrete immunoglobulins known, resulting from the malignant expansion of a normal clone of antibody-producing cells.

References in periodicals archive ?

Fc and Fab and F (ab') 2 fragments were produced from several purified human myeloma proteins of each of the IgG subclasses, by pepsin and papain digestion (16).

Production and characterization of mouse monoclonal antibodies recognizing multiple subclasses of human IgG

The arrays were then washed and blocked with a 5 g/L solution of bovine serum albumin in PBS and incubated for 30 min to 24 h with 50 [micro]L of solution containing human myeloma proteins (Sigma Chemical Co.) diluted in 1 g/L bovine serum albumin.

Mass-sensing, multianalyte microarray immunoassay with imaging detection

Fc, Fab and F (ab') 2 fragments were prepared from several purified human myeloma proteins of each of the IgG subclasses, by pepsin and papain digestion (17).

Generation and characterization of mouse hybridomas secreting monoclonal antibodies specific for human IgG3