In the case of the knee joint, the only medication that has shown benefits with a single infiltration is Synvisc[R]oneTM, unlike the other hyaluronates, which must be infiltrated once a week for 3-5 weeks (Uchoa de Rezende & Constantino de Campos).
However, in physiological conditions it is found in the form of salt, as sodium hyaluronate or hyaluronan; its properties can vary in relation to its molecular weight and shape (Uchoa de Rezende & Constantino de Campos).
Use of sodium hyaluronate in treating temporomandibular joint disorders: a randomized, double-blind, placebo-controlled clinical trial.
Osteoarthritis of the temporomandibular joint: an evaluation of the effects and complications of corticosteroid injection compared with injection with sodium hyaluronate. J.
Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies.
Stitik, "Safety of intraarticular hyaluronates for pain associated with osteoarthritis of the knee," American journal of orthopedics (Belle Mead, N.J.), vol.
In this report, we describe a case of a man who received an intra-articular hyaluronate injection for knee OA and developed a severe articular infection and systemic sepsis.
So he was submitted to an intra-articular hyaluronate injection, without immediate complications.
As mentioned, sodium hyaluronate injection has been proven to be quite safe, with low incidence of adverse reaction [16, 22].
One of these solutions is magnetically controlled viscosupplimentation therapy which aims to restore the viscoelastic qualities of the joint fluid, with concomitant improvement of rheology as a result of controlled degradation of hyaluronate into the joint.
anti-inflammatory effect due to hyaluronate and cortisone derivatives coatings associated with the nanoparticles