human papillomavirus

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Related to Hybrid capture: Hybrid Capture assay

human papillomavirus

(HPV), any of a family of more than 100 viruses that cause various growths, including plantar wartswart,
circumscribed outgrowth of the skin caused by a filterable virus that is readily transmitted. Warts may appear anywhere on the skin but are most common on the hands.
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 and genital warts, a sexually transmitted diseasesexually transmitted disease
(STD) or venereal disease,
term for infections acquired mainly through sexual contact. Five diseases were traditionally known as venereal diseases: gonorrhea, syphilis, and the less common granuloma inguinale, lymphogranuloma venereum, and
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. Genital warts, sometimes called condylomata acuminata, are soft and often occur in clusters. They can occur internally or externally, but even in the absence of warts the virus may be present and transmittable. Problems can result from untreated warts, which can grow quite large, or, in rare cases, from infection of an infant during delivery. In addition, about a dozen strains of HPV are associated with cancercancer,
in medicine, common term for neoplasms, or tumors, that are malignant. Like benign tumors, malignant tumors do not respond to body mechanisms that limit cell growth.
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 of the cervix, vulva, vagina, penis, anus, and mouth and throat, and HPV 16 has been shown to be associated with some forms of Kaposi's sarcoma (see AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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) and throat cancer.

Transmission of HPV strains is often the result of sexual contact, but it can also occur as the result of any skin-to-skin contact involving the mouth or genitals. Detectable warts can be or removed, usually by chemicals, freezing, or laser, but often recur. Intralesional alpha interferon has been effective in the treatment of genital warts. A vaccine approved by the Food and Drug Administration in 2006 can protect a woman against those strains that cause most cases of cervical cancer and genital warts, and a study has shown it may also protect against related throat cancers. HPV vaccination is now recommended for both girls and boys beginning at 11 to 12 years of age.

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human papillomavirus

[¦yü·mən ‚pap·ə′lō·mə ‚vī·rəs]
(medicine)
One of a family of more than 100 different viruses, most commonly spread via sexual contact, that cause warts on the hands and feet and in the genital area; several types are associated with premalignant and malignant changes in the cervix. Abbreviated HPV.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Head-to-Head Comparison of the RNA Based Aptima Human Papillomavirus (HPV) Assay and the DNA-Based Hybrid Capture 2 HPV Test in a Routine Screening Population of Women Aged 30 to 60 Years in Germany.
For 2 samples with IGH-BCL2 rearrangements, sequencing identified the structural variant because of hybrid capture of sequences of BCL2.
[13] Patients who reported back with an abnormal pap as suspicious, that is, atypical squamous cell of undeterminate significance rASCUS) were then subjected to hybrid capture HPV test.
HIV-infected women with positive hybrid capture for CT were younger (18-29 years) than those with a negative test (64.3 vs.
Comparative evaluation of smear cytology & hybrid capture II for the diagnosis of cervical cancer.
In conjunction with the Pap test, the HPV test, which uses DNA-based Hybrid Capture 2 technology to detect HPV, can be used in women over age 30 to help detect HPV infection.
Presently, the two assays most widely used for the detection of genital types are the polymerase chain reaction (PCR) and Hybrid Capture 2 assays (hc2).
For high-risk HPV only the swabs were adequate using one of the laboratory tests (Digene Hybrid Capture II), but both the tampon and swab were acceptable when a second test (Roche Reverse Line Blot Assay) was used.
trachomatis testing using Digene's Hybrid Capture II CT-ID test (Digene Corp., Gaithersburg, Maryland, United States).
Use of a hybrid capture assay of self-collected swabs in rural Uganda for detection of human papilloma virus.
In a separate vote, ACIP also recommended vaccination for women with an equivocal or abnormal Pap test, those who have tested positive for HPV infection using the Hybrid Capture II, and for those with genital warts.