Using a method akin to making a model with a toy construction set, the scientists have created a working hybrid enzyme by connecting individual pieces of other enzymes.
The resulting hybrid enzyme successfully combines functions of the original enzymes.
At the Animal Biosciences and Biotechnology Laboratory in Beltsville, David Donovan showed that hybrid enzymes
, produced by genes that combine activities from two or more phage enzymes, can target and destroy pathogenic bacteria in nature.
Now, with the advent of a new computer technique, FamClash, predictions of hybrid enzymes
possessing high activity can be made to produce enhanced industrial applications and medications.