hybrid molecule

hybrid molecule

[′hī·brəd ′mäl·ə‚kyül]
(biochemistry)
A single molecule, usually protein, peculiar to heterozygotes and containing two structurally different polypeptide chains determined by two different alleles.
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References in periodicals archive ?
The product is a hybrid molecule that includes synthetic peptide carrier and chemotherapy agent, doxorubicin.
Zoptarelin doxorubicin represents a new targeting concept in oncology using a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin.
AEZS-108 represents a new targeting concept in oncology using a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin.
The researchers made use of a unique hybrid molecule, LLP2A-alendronate, that consists of two parts: the LLP2A part that attaches to mesenchymal stem cells in the bone marrow, and a second part that consists of the bone-homing drug alendronate.
The researchers made use of a unique hybrid molecule, LLP2 A-alendronate, that consists of two parts: the LLP2A part that attaches to mesenchymal stem cells in the bone marrow, and a second part that consists of the bone-homing drug alendronate.
Therefore, this is a true hybrid molecule, which appears to have arisen from recombinational events between porB2-99 and porB3-193 alleles.
In addition to the parental cell line preparation, which produced a moderate amount of BCAR1, the study included the transfectant 4A12, which overproduced BCAR1 (1), and transfectants that overproduced FLAG-tagged (Stratagene Europe) BCAR1 (FBCAR1), HEF1, and a FLAG-tagged hybrid molecule consisting of the first 63 amino acid residues of BCAR1 and residues 64-834 of HEF1 (F-Hybrid).
The ZoptEC pivotal Phase 3 trial was a fully-recruited (512 patients), open-label, randomised-controlled study, comparing the efficacy and safety of zoptarelin doxorubicin, a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin, to doxorubicin alone.
Phenalkamide: New Hybrid Molecule and Its Unique Coating Properties--Yun Mi Kim, Cardolite
One did, quite convincingly - a hybrid molecule, which researchers named JQ1, for Qi.
The mix-up causes the cells to make a hybrid molecule consisting of parts of two separate immune system proteins, presumably because pieces of the proteins' respective genes have fused.
A phybrid is a peptide hybrid molecule that combines the pharmacological effects of two peptide hormones into a single molecular entity.

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