hybrid molecule

hybrid molecule

[′hī·brəd ′mäl·ə‚kyül]
(biochemistry)
A single molecule, usually protein, peculiar to heterozygotes and containing two structurally different polypeptide chains determined by two different alleles.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
The hybrid molecule is made up of part modified testosterone and part progestin and would ensure that the person taking the pill always has matching levels of the hormones in their body.
The product is a hybrid molecule that includes synthetic peptide carrier and chemotherapy agent, doxorubicin.
Zoptarelin doxorubicin represents a new targeting concept in oncology using a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin.
AEZS-108 represents a new targeting concept in oncology using a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin.
The researchers made use of a unique hybrid molecule, LLP2A-alendronate, that consists of two parts: the LLP2A part that attaches to mesenchymal stem cells in the bone marrow, and a second part that consists of the bone-homing drug alendronate.
The researchers made use of a unique hybrid molecule, LLP2 A-alendronate, that consists of two parts: the LLP2A part that attaches to mesenchymal stem cells in the bone marrow, and a second part that consists of the bone-homing drug alendronate.
Therefore, this is a true hybrid molecule, which appears to have arisen from recombinational events between porB2-99 and porB3-193 alleles.
In addition to the parental cell line preparation, which produced a moderate amount of BCAR1, the study included the transfectant 4A12, which overproduced BCAR1 (1), and transfectants that overproduced FLAG-tagged (Stratagene Europe) BCAR1 (FBCAR1), HEF1, and a FLAG-tagged hybrid molecule consisting of the first 63 amino acid residues of BCAR1 and residues 64-834 of HEF1 (F-Hybrid).
The ZoptEC pivotal Phase 3 trial was a fully-recruited (512 patients), open-label, randomised-controlled study, comparing the efficacy and safety of zoptarelin doxorubicin, a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin, to doxorubicin alone.
Phenalkamide: New Hybrid Molecule and Its Unique Coating Properties--Yun Mi Kim, Cardolite
One did, quite convincingly - a hybrid molecule, which researchers named JQ1, for Qi.
The mix-up causes the cells to make a hybrid molecule consisting of parts of two separate immune system proteins, presumably because pieces of the proteins' respective genes have fused.