hybridoma


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hybridoma

[‚hī·brə′dō·mə]
(immunology)
A hybrid myeloma formed by fusing myeloma cells with lymphocytes that produce a specific antibody; the individual cells can be cloned, and each clone produces large amounts of identical (monoclonal) antibody.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Antibodies were depleted from the hybridoma supernatant by the indicated procedures.
Anti-Plexin C1 monoclonal antibodies were purified from hybridoma supernatants on AKTA-Purifier Chromatography (GE, Massachusetts, USA) using protein G affinity column (HiTrap protein G, GE).
In addition, all hybridoma supernatants were tested against parainfluenza virus (negative control) respiratory tract cell antigens at the same concentration, with overnight incubation at 4 [degrees]C.
Keywords: Domoic acid, Amnesic shellfish poisoning, Cell culture, Hybridoma, Monoclonal antibody, Fetal bovine medium, Carbohydrates.
and Jessell, T, respectively, were obtained from the Developmental Studies Hybridoma Bank, created by the NICHD of the NIH and maintained at Department of Biology, The University of Iowa, Iowa City, IA 52242.
Then, hybridoma supernatant was added to the plates, and incubated for 12 h at 4[degrees]C.
The effect of hybridoma concentration on the yield of antibody-producing clones.
The living substrate may be genetically modified in a number of ways to provide the required active ingredient, including recombinant DNA technology or hybridoma techniques.
The study of activity of AIAT produced by them with the help of ELISA test revealed that AIAT produced by the 2D9, 2G9 hybridoma cells preserved their activity.
(1,7,11-18) We herein describe the development of a new mouse monoclonal SOX10 hybridoma (BC34) and evaluate its sensitivity and specificity in normal and neoplastic tissues, with an emphasis on melanoma and its subtypes.
Experimental support was provided by the Hybridoma Facility of the Rheumatic Diseases Core Center.