Hydatiform Mole

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hydatiform mole

[hī′dad·ə‚fȯrm ′mōl]
(medicine)
A benign placental tumor formed as a cystic growth of the chorionic villi. Also known as hydatiform tumor.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Hydatiform Mole

 

an abnormal pregnancy resulting from a pathologic ovum with proliferation of the epithelium of the chorion frondosum and edema of the stroma of the villi. The causes of a hydatiform mole are not known. Externally it resembles a grape cluster, since it is a cluster of variously sized cysts with transparent contents.

When there is a hydatiform mole and changes in the villi are widespread, the fetus most often dies; however, even after the death of the fetus the mole continues to develop. As a result of proliferation of the vesicles, the uterus enlarges comparatively rapidly, and its size does not correspond to the term of the pregnancy. One of the principal symptoms of a hydatiform mole is the appearance in the third or fourth month of pregnancy of bloody discharges and hemorrhages from the genital tract, which result from the partial sloughing off of cysts from the uterine walls. The blood is watery and dark in color and contains the rejected cysts of the mole. Hemorrhage leads to considerable anemia and may endanger the woman’s life if intensified.

Often when there is a hydatiform mole, symptoms of late toxemia of pregnancy appear as early as the first half of the pregnancy. In the rare invasive form of hydatiform mole the cysts deeply penetrate the musculature of the uterus, which may lead to perforation of the uterus and severe intra-abdominal hemorrhage. The greatest danger of an hydatiform mole is the possible development of a malignant tumor, that is, a chorionepithelioma.

Treatment includes the use of preparations that contract the uterus. The cysts of the mole can also be sucked out with a special vacuum apparatus. After removal of a hydatiform mole the woman remains under a doctor’s care for 1½ to two years.

A. P. KIRIUSHCHENKOV

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Ninety percent of cases are secondary to hydatidiform mole (HM), which is classically a benign, noninvasive tumor with an excess of paternal chromosomes [3].
Risk of recurrent hydatidiform mole and subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy.
Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole. J Reprod Med 2004; 49:630-36.
Now I address three problems for the suggestions I am making: (1) the hydatidiform mole, (2) the zygote's requirement for maternal cytoplasm, (3) and the problem of totipotentiality (including twinning).
Histologic review confirmed complete hydatidiform mole. She had minimal vaginal bleeding in the postoperative period and her hemoglobin was 9.3 g/dL.
Given the absence of referent histopathologist in GTD in Morocco, this surveillance scheme was adopted for both complete hydatidiform moles (CHM) and partial hydatidiform moles (PHM) to ensure higher security for patients and avoid the consequences of a potential underestimated diagnosis.
We recorded all cases with hydatidiform mole. Data Processing and statistical analysis were performed using SPSS version 16.0.
False-negative pregnancy test in hydatidiform mole. Clin Chem 2006; 52:1616-8.
Complete hydatidiform mole is the most common of these entities.
Invasive hydatidiform mole presnting as acute primary haemoperitoneum.
Background: Hydatidiform mole is an abnormal gestation characterized by trophoblastic hyperplasia and overgrowth of placental villi.